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Human C5aR1 VLP (C5R-HM00V) Summary
Product Description |
Recombinant Human C5aR1 VLP is expressed from HEK293.It contains Met1-Val350 (It may have cross reaction with anti-His antibody). |
Product Background |
C5a receptor 1 (C5aR1), a membrane-bound G protein-coupled receptor (GPCR), is the most commonly studied C5a receptor. The complement system is an important constituent of the innate immune response, and it regulates humoral immunity and pathogen immune surveillance and maintains tissue homeostasis. The C5a/C5aR1 activation pathway has been implicated in various inflammatory processes, the pathogenesis of immune diseases, and tumor growth. |
Product Category |
Recombinant Protein / Antibody discovery / Multiple transmembrane proteins / VLP |
Human C5aR1 VLP (C5R-HM00V) Specifications/Details
Protein |
C5aR1 |
Synonyms |
C5a-R; C5aR; CD88; C5R1; C5A; C5a Ligand |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Met1-Val350 |
Molecular Weight |
The target protein has a predicted MW of 42.55 kDa. |
Activity |
Immobilized Human C5aR1 VLP at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-C5aR1 Antibody, hFc Tag with the EC50 of 17.3ng/ml determined by ELISA. |
Fluorophore |
Unconjugated |
Expression System |
HEK293 |
Purity |
> 95% as determined by HPLC |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22 um filtered solution in PBS, 300mM L-arginine (pH 7.4). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Validation Images
|
|
Immobilized Human C5aR1 VLP at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-C5aR1 Antibody, hFc Tag with the EC50 of 17.3ng/ml determined by ELISA. |
|
|
The purity of Human C5aR1 VLP is greater than 95% as determined by SEC-HPLC. |
Other Available Proteins:
Finding available proteins...
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