Name: Human CA125/MUC16 Protein, Ultra Low Endotoxin (MUC-HM416-UL)
Brand: KactusBio
SKU: MUC-HM416-UL-100UG
Price: 381.0 USD
Availability: InStock

Human CA125/MUC16 Protein, Ultra Low Endotoxin (MUC-HM416-UL)

Immobilized Human CA125, His Tag at 5ug/ml (100ul/Well) on the plate. Dose response curve for Human MSLN, hFc Tag with the EC50 of 1.13ug/ml determined by ELISA.

Human CA125 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Human CA125 is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-His-Avi
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Human CA125, His Tag at 5ug/ml (100ul/Well) on the plate. Dose response curve for Human MSLN, hFc Tag with the EC50 of 1.13ug/ml determined by ELISA. See testing image for detail.
Amino Acid Range: Gly12660-Met12923

Catalog #MUC-HM416-UL

Size

100UG

500UG

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Product Description	Recombinant Human CA125/MUC16 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Gly12660-Met12923.
Product Background	MUC16, also known as the CA125 antigen, is a mucin protein that may be found in type I transmembrane or secreted forms that are used monitor the progress of epithelial ovarian cancer therapy.Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces.Binding to MSLN mediates heterotypic cell adhesion. This may contribute to the metastasis of ovarian cancer to the peritoneum by initiating cell attachment to the mesothelial epithelium via binding to MSLN.
Product Category	Recombinant Protein / Antibody discovery / CAR-T targets

Protein	CA125/MUC16
Synonyms	CA125; CA-125; CA125MUC-16; FLJ14303; MUC16
Accession	Q8WXI7
Species	Human
Biotinylated	no
Amino Acid Range	Gly12660-Met12923
Molecular Weight	The protein has a predicted MW of 31.3 kDa. Due to glycosylation, the protein migrates to 55-70 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human CA125, His Tag at 5ug/ml (100ul/Well) on the plate. Dose response curve for Human MSLN, hFc Tag with the EC50 of 1.13ug/ml determined by ELISA. See testing image for detail.
Product Tag	C-His-Avi
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 0.001 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human CA125, His Tag at 5ug/ml (100ul/Well) on the plate. Dose response curve for Human MSLN, hFc Tag with the EC50 of 1.13ug/ml determined by ELISA.
	Human CA125 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human CA125 is greater than 95% as determined by SEC-HPLC.