Human CADM1/IGSF4A Protein (CAD-HM101)

  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Human CADM1, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-CADM1 Antibody, hFc Tag with the EC50 of 4.0g/ml determined by ELISA. See testing image for detail.
  • Exact Sequence: Gln45-His374

Catalog: CAD-HM101

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Product Description Recombinant Human CADM1/IGSF4A Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln45-His374.

Product Background

The cell adhesion molecule 1 (CADM1) is a molecule of cell adhesion with multiple functions and has been identified as a tumor suppressor gene. CADM1 has multifunctions on the pathogenesis of malignancies, and other normal cells such as immune cells. On the contrary to these cutaneous solid tumors except for Merkel cell carcinoma, cutaneous lymphomas, such as adult-T cell leukemia/lymphoma, mycosis fungoides, and Sézary syndrome, increase their CADM1 expression for the development of tumor environment.

Product Category

Recombinant Protein

Target

CADM1/IGSF4A
Synonyms IgSF4; NECL-2; SgIgSF; SynCAM; TSLC-1; Cadm1; BL2; IGSF4; IGSF4A; RA175; ST17; TSLC1; sTSLC-1; sgIGSF; synCAM1; BL2; NECL2

Gene/Protein ID

Q9BY67-1

Species

Human

Exact Sequence

Gln45-His374
Molecular Weight The protein has a predicted MW of 38 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.

Activity

Immobilized Human CADM1, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-CADM1 Antibody, hFc Tag with the EC50 of 4.0g/ml determined by ELISA. See testing image for detail.

Product Tag

C-His

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Immobilized Human CADM1, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-CADM1 Antibody, hFc Tag with the EC50 of 4.0g/ml determined by ELISA.
The purity of Human CADM1 is greater than 95% as determined by SEC-HPLC.
Human CADM1 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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