HPLC chromatogram showing purity analysis of a recombinant protein sample with a main peak around 10 minutes and minor impurity peaks, reflecting overall high purity with trace contaminants.
Human CCL11 Protein (CCL-HE111)
Human CCL11 Protein (CCL-HE111)
  • Express System: E.coli
  • Product Tag: N-His
  • Purity: > 95% as determined by Bis-Tris PAGE
  • Amino Acid Range: Gly24-Pro97
Catalog #CCL-HE111
Regular price $330.00
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Size
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Human CCL11 Protein (CCL-HE111) Summary

Product Description

Recombinant Human CCL11 Protein is expressed from E.coli with His tag at the N-Terminus.It contains Gly24-Pro97.

Product Background

The chemokine CCL11 (also known as eotaxin-1) is a potent eosinophil chemoattractant that mediates allergic diseases such as asthma, atopic dermatitis, and inflammatory bowel diseases. CCL11 released from activated astrocytes triggers oxidative stress via microglial NOX1 activation and potentiates glutamate-mediated neurotoxicity, which may be involved in the pathogenesis of various neurological disorders.

Product Category

Recombinant Protein / Antibody discovery / Antibody discovery | Others

Human CCL11 Protein (CCL-HE111) Specifications/Details

Protein
CCL11
Synonyms
Eotaxin; C-C motif chemokine 11; Small-inducible cytokine A11; SCYA11; eotaxin-1
Accession
Species
Human
Biotinylated
no
Amino Acid Range
Gly24-Pro97
Molecular Weight
The protein has a predicted MW of 9.46 kDa. The protein migrates to 13-15 kDa based on Bis-Tris PAGE result.
Product Tag
N-His

Fluorophore

Unconjugated
Expression System
E.coli
Purity
> 95% as determined by Bis-Tris PAGE
Endotoxin
Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
Liquid
Shipping
Shipped with dry ice.
Formulation
Supplied as 0.22um filtered solution in 20mM PB, 500mM NaCl, 200mM L-arginine (pH 7.4).
Stability And Storage
Valid for 12 months from date of receipt when stored at -80°C.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Human CCL11 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human CCL11 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
Other Available Proteins:
Finding available proteins...
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