Name: Human CCL11 Protein (CCL-HE111)
Brand: KactusBio
SKU: CCL-HE111-100UG
Price: 300.0 USD
Availability: InStock

Catalog #CCL-HE111

Size

100UG

500UG

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Product Description	Recombinant Human CCL11 Protein is expressed from E.coli with His tag at the N-Terminus.It contains Gly24-Pro97.
Product Background	The chemokine CCL11 (also known as eotaxin-1) is a potent eosinophil chemoattractant that mediates allergic diseases such as asthma, atopic dermatitis, and inflammatory bowel diseases. CCL11 released from activated astrocytes triggers oxidative stress via microglial NOX1 activation and potentiates glutamate-mediated neurotoxicity, which may be involved in the pathogenesis of various neurological disorders.
Product Category	Recombinant Protein / Antibody discovery

Protein	CCL11
Synonyms	Eotaxin; C-C motif chemokine 11; Small-inducible cytokine A11; SCYA11; eotaxin-1
Accession	P51671
Species	Human
Biotinylated	no
Amino Acid Range	Gly24-Pro97
Molecular Weight	The protein has a predicted MW of 9.46 kDa. The protein migrates to 13-15 kDa based on Bis-Tris PAGE result.
Product Tag	N-His
Expression System	E.coli
Purity	> 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22um filtered solution in 20mM PB, 500mM NaCl, 200mM L-arginine (pH 7.4).
Stability And Storage	Valid for 12 months from date of receipt when stored at -80°C.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Human CCL11 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human CCL11 is greater than 90% as determined by SEC-HPLC.