Human CCL11 Protein (CCL-HE111)

  • Express System: E.coli
  • Product Tag: N-His
  • Purity: > 95% as determined by Tris-Bis PAGE;> 90% as determined by HPLC
  • Exact Sequence: Gly24-Pro97

Catalog: CCL-HE111

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Product Description Recombinant Human CCL11 Protein is expressed from E.coli with His tag at the N-Terminus.It contains Gly24-Pro97.

Product Background

 The chemokine CCL11 (also known as eotaxin-1) is a potent eosinophil chemoattractant that mediates allergic diseases such as asthma, atopic dermatitis, and inflammatory bowel diseases. CCL11 released from activated astrocytes triggers oxidative stress via microglial NOX1 activation and potentiates glutamate-mediated neurotoxicity, which may be involved in the pathogenesis of various neurological disorders.

Product Category

 Recombinant Protein

Target

 CCL11

Gene/Protein ID

 P51671

Species

 Human

Exact Sequence

 Gly24-Pro97
Molecular Weight The protein has a predicted MW of 9.46 kDa. The protein migrates to 13-15 kDa based on Tris-Bis PAGE result.

Product Tag

 N-His

Express System

 E.coli
Purity > 95% as determined by Tris-Bis PAGE;> 90% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Liquid
Shipping Shipped with dry ice.
Formulation Supplied as 0.22um filtered solution in 20mM PB, 500mM NaCl, 200mM L-arginine (pH 7.4).
Stability And Storage Valid for 12 months from date of receipt when stored at -80°C.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
The purity of Human CCL11 is greater than 90% as determined by SEC-HPLC.
Human CCL11 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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