Product Description |
Recombinant Human CCR2b Protein-VLP is expressed from HEK293.It contains Met1-Leu360. |
Product Background |
The chemokine (C-C motif) receptor 2B (CCR2B) is one of the two isoforms of the receptor for monocyte chemoattractant protein-1 (CCL2), the major chemoattractant for monocytes, involved in an array of chronic inflammatory diseases. The actin-binding protein filamin A (FLNa) as a protein that associates with the carboxyl-terminal tail of CCR2B. FLNa emerges as an important protein for controlling the internalization and spatial localization of the CCR2B receptor in different dynamic membrane structures. |
Product Category |
Recombinant Protein / Antibody discovery / Multiple transmembrane proteins / VLP |
Protein |
CCR2b |
Synonyms |
C-C CKR-2; CCR-2; CCR2; MCP-1-R; CMKBR2; CCR2 |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Met1-Leu360 |
Molecular Weight |
The target protein has a predicted MW of 42.9kDa. |
Activity |
Immobilized Human CCR2b VLP at 5ug/ml (100ul/Well) on the plate. Dose response curve for Anti-CCR2b Antibody, hFc Tag with the EC50 of 0.11ug/ml determined by ELISA. See testing image for detail. |
Expression System |
HEK293 |
Purity |
> 95% as determined by HPLC |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22um filtered solution in PBS, 300mM L-Arginine (pH 7.4). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
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Immobilized Human CCR2b VLP at 5ug/ml (100ul/Well) on the plate. Dose response curve for Anti-CCR2b Antibody, hFc Tag with the EC50 of 0.11ug/ml determined by ELISA. |
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The purity of Human CCR2b VLP is greater than 95% as determined by SEC-HPLC. |
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