Name: Human CCR7 Protein-Nanodisc (CCR-HM107)
Brand: KactusBio
SKU: CCR-HM107-100UG
Price: 1210.0 USD
Availability: InStock

Express System: HEK293
Product Tag: C-His
Activity: Immobilized Human CCR7 Nanodisc, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-CCR7 Antibody, hFc Tag with the EC50 of 0.21ug/ml determined by ELISA (QC Test). The affinity constant of 4.11 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Amino Acid Range: Met1-Pro378

Catalog #CCR-HM107

Size

100UG

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Product Description	Recombinant Human CCR7 Protein-Nanodisc is expressed from HEK293 with His tag at the C-terminus (FITC-equivalent protein is fused on cytoplasmic part).It contains Met1-Pro378.
Product Background	CC-chemokine receptor 7 (CCR7), collaborated with its ligands CCL19 and CCL21, controls extensive migratory events in the immune system. CCR7-bearing dendritic cells can swarm into T-cell zones in lymph nodes, initiating the antigen presentation and T-cell response. Abnormal expression of CCR7 in dendritic cells will cause a series of inflammatory diseases due to the chaotic dendritic cell trafficking.
Product Category	Recombinant Protein / Antibody discovery / Multiple transmembrane proteins / Nanodisc

Protein	CCR7
Synonyms	CCR7; C-C CKR-7; CC-CKR-7; CCR-7; BLR2; CDw197; EBI1; CD197; CMKBR7; EBI1; EVI1
Accession	P32248
Species	Human
Biotinylated	no
Amino Acid Range	Met1-Pro378
Molecular Weight	The protein has a predicted MW of 67.70 kDa.
Activity	Immobilized Human CCR7 Nanodisc, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-CCR7 Antibody, hFc Tag with the EC50 of 0.21ug/ml determined by ELISA (QC Test). The affinity constant of 4.11 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Product Tag	C-His
Expression System	HEK293
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22 um filtered solution in PBS (pH 7.4). Notice: Not recommended for flow cytometry in mammalian cells.
Stability And Storage	Valid for 6 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Human CCR7 Nanodisc, His Tag captured on CM5 Chip via Anti-his antibody can bind Anti-CCR7 Antibody, hFc Tag with an affinity constant of 4.11 nM as determined in SPR assay (Biacore T200).
	Immobilized Human CCR7 Nanodisc, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-CCR7 Antibody, hFc Tag with the EC50 of 0.21ug/ml determined by ELISA (QC Test).