Human CCR7 Protein-Nanodisc (CCR-HM107)

Express System: HEK293
Product Tag: C-His
Activity: Immobilized Human CCR7 (Nanodisc), His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-CCR7 Antibody, hFc Tag with the EC50 of 0.21ug/ml determined by ELISA (QC Test). The affinity constant of 4.11 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Exact Sequence: Met1-Pro378

Catalog: CCR-HM107

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Product Description	Recombinant Human CCR7 Protein-Nanodisc is expressed from HEK293 with His tag at the C-terminus.It contains Met1-Pro378.
Product Background	CC-chemokine receptor 7 (CCR7), collaborated with its ligands CCL19 and CCL21, controls extensive migratory events in the immune system. CCR7-bearing dendritic cells can swarm into T-cell zones in lymph nodes, initiating the antigen presentation and T-cell response. Abnormal expression of CCR7 in dendritic cells will cause a series of inflammatory diseases due to the chaotic dendritic cell trafficking.
Product Category	Recombinant Protein

Target	CCR7
Gene/Protein ID	P32248
Species	Human
Exact Sequence	Met1-Pro378
Molecular Weight	The protein has a predicted MW of 67.70 kDa.
Activity	Immobilized Human CCR7 (Nanodisc), His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-CCR7 Antibody, hFc Tag with the EC50 of 0.21ug/ml determined by ELISA (QC Test). The affinity constant of 4.11 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Product Tag	C-His
Express System	HEK293

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage	Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Human CCR7 (Nanodisc), His Tag captured on CM5 Chip via Anti-his antibody can bind Anti-CCR7 Antibody, hFc Tag with an affinity constant of 4.11 nM as determined in SPR assay (Biacore T200).
	Immobilized Human CCR7 (Nanodisc), His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-CCR7 Antibody, hFc Tag with the EC50 of 0.21ug/ml determined by ELISA (QC Test).