FITC-equivalent Human CCR7 Protein-Nanodisc (CCR-HM107)
FITC-equivalent Human CCR7 Protein-Nanodisc (CCR-HM107)
FITC-equivalent Human CCR7 Protein-Nanodisc (CCR-HM107)
  • Express System: HEK293
  • Product Tag: C-His
  • Activity: Immobilized FITC-equivalent Human CCR7 Nanodisc, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-CCR7 Antibody, hFc Tag with the EC50 of 0.21ug/ml determined by ELISA (QC Test). The affinity constant of 4.11 nM as determined in SPR assay (Biacore T200). See testing image for detail.
  • Amino Acid Range: Met1-Pro378
Catalog #CCR-HM107
Regular price $1,100.00
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Product Description
Recombinant FITC-equivalent Human CCR7 Protein-Nanodisc is expressed from HEK293 with His tag at the C-terminus.It contains Met1-Pro378.
Product Background
CC-chemokine receptor 7 (CCR7), collaborated with its ligands CCL19 and CCL21, controls extensive migratory events in the immune system. CCR7-bearing dendritic cells can swarm into T-cell zones in lymph nodes, initiating the antigen presentation and T-cell response. Abnormal expression of CCR7 in dendritic cells will cause a series of inflammatory diseases due to the chaotic dendritic cell trafficking.
Product Category
Recombinant Protein
Target
CCR7
Accession
Species
Human
Biotinylated
no
Amino Acid Range
Met1-Pro378
Molecular Weight
The protein has a predicted MW of 67.70 kDa.
Activity
Immobilized FITC-equivalent Human CCR7 Nanodisc, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-CCR7 Antibody, hFc Tag with the EC50 of 0.21ug/ml determined by ELISA (QC Test). The affinity constant of 4.11 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Product Tag
C-His
Fluorophore
FITC
Express System
HEK293
Endotoxin
Less than 1EU per ug by the LAL method.
Form
Liquid
Shipping
Shipped with dry ice.
Formulation
Supplied as 0.22 um filtered solution in PBS (pH 7.4). Notice: Not recommended for immunization.
Stability And Storage
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
FITC-equivalent Human CCR7 Nanodisc, His Tag captured on CM5 Chip via Anti-his antibody can bind Anti-CCR7 Antibody, hFc Tag with an affinity constant of 4.11 nM as determined in SPR assay (Biacore T200).
Immobilized FITC-equivalent Human CCR7 Nanodisc, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-CCR7 Antibody, hFc Tag with the EC50 of 0.21ug/ml determined by ELISA (QC Test).

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