Human CCR7 (nanodisc) Protein (CCR-HM107)
Catalog: CCR-HM107
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Product Description | Recombinant Human CCR7 (nanodisc) Protein is expressed from HEK293 with His tag at the C-terminus.It contains Met1-Pro378. |
Product Background |
CC-chemokine receptor 7 (CCR7), collaborated with its ligands CCL19 and CCL21, controls extensive migratory events in the immune system. CCR7-bearing dendritic cells can swarm into T-cell zones in lymph nodes, initiating the antigen presentation and T-cell response. Abnormal expression of CCR7 in dendritic cells will cause a series of inflammatory diseases due to the chaotic dendritic cell trafficking. |
Product Category |
Recombinant Protein |
Target |
CCR7 (nanodisc) |
Gene/Protein ID |
P32248 |
Species |
Human |
Exact Sequence |
Met1-Pro378 |
Molecular Weight | The protein has a predicted MW of 67.70 kDa. |
Activity |
Immobilized Human CCR7 nanodisc, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-CCR7 Antibody, hFc Tag with the EC50 of 0.21ug/ml determined by ELISA. See testing image for detail. |
Product Tag |
C-His |
Express System |
HEK293 |
Endotoxin | Less than 1EU per ug by the LAL method. |
Form | Liquid |
Shipping | Shipped with dry ice. |
Formulation | Supplied as 0.22 um filtered solution in PBS (pH 7.4). |
Stability And Storage | Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
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