Human CD13/ANPEP Protein (ANP-HM101)
Human CD13/ANPEP Protein (ANP-HM101)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Lys69-Lys967
Catalog #ANP-HM101
Regular price $300.00
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Product Description
Recombinant Human CD13/ANPEP Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Lys69-Lys967.
Product Background
CD13/aminopeptidase N is a widely expressed ectoenzyme with multiple functions. As an enzyme, CD13 regulates activities of numerous cytokines by cleaving their N-terminals and is involved in Ag processing by trimming the peptides bound to MHC class II. Independent of its enzymatic activity, cell membrane CD13 functions by cross-linking-induced signal transduction, regulation of receptor recycling, enhancement of FcγR-mediated phagocytosis, and acting as a receptor for cytokines.
Product Category
Recombinant Protein
Target
CD13/ANPEP
Synonyms
Aminopeptidase N; AP-N; Alanyl aminopeptidase; Aminopeptidase M; AP-M; ANPEP; APN; CD13; PEPN; Cd13; CD13APN; EC 3.4.11; EC 3.4.11.2; gp150; LAP1; PEPNhAPN
Accession
Species
Human
Biotinylated
no
Amino Acid Range
Lys69-Lys967
Molecular Weight
The protein has a predicted MW of 103.8 kDa. Due to glycosylation, the protein migrates to 115-130 kDa based on Bis-Tris PAGE result.
Product Tag
C-His
Express System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Human CD13/ANPEP on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human CD13/ANPEP is greater than 95% as determined by SEC-HPLC.
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