Human CD155/PVR Protein (CD1-HM355)
Human CD155/PVR Protein (CD1-HM355)
  • Express System: HEK293
  • Product Tag: C-mFc
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Human CD155, mFc Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Human TIGIT, hFc Tag with the EC50 of 0.13ug/ml determined by ELISA (QC Test).
  • Amino Acid Range: Trp21-Asn343
Catalog #CD1-HM355
Regular price $264.00
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Size
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Human CD155/PVR Protein (CD1-HM355) Summary

Product Description

Recombinant Human CD155/PVR Protein is expressed from HEK293 with mFc (IgG1) tag at the C-Terminus.It contains Trp21-Asn343.

Product Background

CD155 is a cell surface adhesion molecule functioning in tumor cell migration, invasion, and metastasis, and not surprisingly, is also designated as a common tumor-associated antigen. CD155 is also recognized by NK cells to induce their cytotoxicity. CD155 is also commonly referred to as the "poliovirus receptor," or PVR.

Product Category

Recombinant Protein / Antibody discovery / Immune checkpoint proteins

Human CD155/PVR Protein (CD1-HM355) Specifications/Details

Protein
CD155/PVR
Synonyms
CD155; HVED; NECL5; Necl-5; nectin-like 5; PVR; PVS; Tage4; PVSFLJ25946; FLJ25946
Accession
Species
Human
Biotinylated
no
Amino Acid Range
Trp21-Asn343
Molecular Weight
The protein has a predicted MW of 61.3 kDa. Due to glycosylation, the protein migrates to 75-100 kDa based on Bis-Tris PAGE result.
Activity
Immobilized Human CD155, mFc Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Human TIGIT, hFc Tag with the EC50 of 0.13ug/ml determined by ELISA (QC Test).
Product Tag
C-mFc

Fluorophore

Unconjugated
Expression System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Immobilized Human CD155, mFc Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Human TIGIT, hFc Tag with the EC50 of 0.13ug/ml determined by ELISA (QC Test). Immobilized Human CD155, mFc Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Human TIGIT, hFc Tag with the EC50 of 0.13ug/ml determined by ELISA (QC Test).
Immobilized Human DNAM-1, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human CD155, mFc Tag with the EC50 of 0.45ug/ml determined by ELISA. Immobilized Human DNAM-1, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human CD155, mFc Tag with the EC50 of 0.45ug/ml determined by ELISA.
Human CD155 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human CD155 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human CD155 is greater than 95% as determined by SEC-HPLC. The purity of Human CD155 is greater than 95% as determined by SEC-HPLC.
Other Available Proteins:
Finding available proteins...
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