Human CD161 Protein (CD1-HM261)

  • Express System: HEK293
  • Product Tag: C-hFc
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Human CD161, hFc Tag at 0.5ug/ml (100ul/Well) on the plate. Dose response curve for Biotinylated Anti-CD161 Antibody, hFc Tag with the EC50 of 24.3ng/ml determined by ELISA. See testing image for detail.
  • Exact Sequence: Gln67-Ser225

Catalog: CD1-HM261

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Product Description Recombinant Human CD161 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Gln67-Ser225.

Product Background

CD161 (NKRP1) is a lectin-like receptor present on NK cells and rare T-cell subsets. We have observed CD161 expression in some cases of T-cell prolymphocytic leukemia (T-PLL) and found it to be useful in follow-up and detection of disease after treatment.

Product Category

Recombinant Protein

Target

CD161
Synonyms KLRB1; CLEC5B; NKRP1A; NKR-P1A; HNKR-P1a; CD161; Ly59; NKR; NKRP1; NKR-P1; NKRP1ANKR

Gene/Protein ID

Q12918-1

Species

Human

Exact Sequence

Gln67-Ser225
Molecular Weight The protein has a predicted MW of 45.2 kDa. Due to glycosylation, the protein migrates to 65-68 kDa based on Tris-Bis PAGE result.

Activity

Immobilized Human CD161, hFc Tag at 0.5ug/ml (100ul/Well) on the plate. Dose response curve for Biotinylated Anti-CD161 Antibody, hFc Tag with the EC50 of 24.3ng/ml determined by ELISA. See testing image for detail.

Product Tag

C-hFc

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Immobilized Human CD161, hFc Tag at 0.5ug/ml (100ul/Well) on the plate. Dose response curve for Biotinylated Anti-CD161 Antibody, hFc Tag with the EC50 of 24.3ng/ml determined by ELISA.
The purity of Human CD161 is greater than 93% as determined by SEC-HPLC.
Human CD161 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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