• Express System: HEK293
  • Purity: > 95% as determined by HPLC
  • Activity: Immobilized Human CD19 VLP at 2 ug/ml (100ul/well) on the plate. Dose response curve for Coltuximab, hFc Tag with the EC50 of 4.9ng/ml determined by ELISA.
  • Amino Acid Range: Met1-Arg556
Catalog #CD1-HM09V
Price
Regular price $1,21000
Regular price Sale price $1,21000
/
Size
Avantor VWR Fisher Scientific

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Human CD19 VLP (CD1-HM09V) Summary

Product Description

 Human CD19 VLP is expressed from HEK293. It contains Met1-Arg556 (It may have cross reaction with anti-His antibody).

Product Background

 CD19 is a 95 kDa transmembrane glycoprotein that plays a central role in B cell activation and humoral immune responses. Functions as coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens. Activates signaling pathways that lead to the activation of phosphatidylinositol 3-kinase and the mobilization of intracellular Ca2 stores.

Human CD19 VLP (CD1-HM09V) Specifications/Details

Protein
 CD19
Synonyms
 CD19; B4; CVID3; Leu-12; MGC12802;Leu12
Accession
Species
 Human
Biotinylated
 no
Amino Acid Range
 Met1-Arg556
Molecular Weight
 The target protein has a predicted MW of 62.04 kDa.
Activity
 Immobilized Human CD19 VLP at 2 ug/ml (100ul/well) on the plate. Dose response curve for Coltuximab, hFc Tag with the EC50 of 4.9ng/ml determined by ELISA.
Fluorophore
 Unconjugated
Expression System
 HEK293
Purity
 > 95% as determined by HPLC
Endotoxin
 Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
 Liquid
Shipping
 Shipped with dry ice.
Formulation
 Supplied as 0.22 um filtered solution in PBS, 300mM L-arginine (pH 7.4). Notice: If you need it for immunization, water-soluble adjuvant is recommended.
Stability And Storage
 Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Immobilized Human CD19 VLP at 2 ug/ml (100ul/well) on the plate. Dose response curve for Coltuximab, hFc Tag with the EC50 of 4.9ng/ml determined by ELISA. Immobilized Human CD19 VLP at 2 ug/ml (100ul/well) on the plate. Dose response curve for Coltuximab, hFc Tag with the EC50 of 4.9ng/ml determined by ELISA.
Immobilized Human CD19 VLP at 2ug/ml (100ul/well) on the plate. Dose response curve for FMC63, mFc Tag with the EC50 of 4.0/-ng/ml determined by ELISA. Immobilized Human CD19 VLP at 2ug/ml (100ul/well) on the plate. Dose response curve for FMC63, mFc Tag with the EC50 of 4.0/-ng/ml determined by ELISA.
Immobilized Human CD19 VLP at 2ug/ml (100ul/well) on the plate. Dose response curve for Inebilizumab, hFc Tag with the EC50 of 4.3ng/ml determined by ELISA. Immobilized Human CD19 VLP at 2ug/ml (100ul/well) on the plate. Dose response curve for Inebilizumab, hFc Tag with the EC50 of 4.3ng/ml determined by ELISA.
Immobilized Human CD19 VLP at 2ug/ml (100ul/well) on the plate. Dose response curve for Denintuzumab, hFc Tag with the EC50 of 10.9ng/ml determined by ELISA. Immobilized Human CD19 VLP at 2ug/ml (100ul/well) on the plate. Dose response curve for Denintuzumab, hFc Tag with the EC50 of 10.9ng/ml determined by ELISA.
The purity of Human CD19 VLP is greater than 95% as determined by SEC-HPLC. The purity of Human CD19 VLP is greater than 95% as determined by SEC-HPLC.
Other Available Proteins:
Finding available proteins...