Human CD19 VLP (CD1-HM09V)

Express System: HEK293
Purity: > 95% as determined by HPLC
Activity: Immobilized Human CD19 VLP at 2 ug/ml (100ul/well) on the plate. Dose response curve for Coltuximab, hFc Tag with the EC50 of 4.9ng/ml determined by ELISA.
Amino Acid Range: Met1-Arg556

Catalog #CD1-HM09V

Price

$1,210.00

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Human CD19 VLP (CD1-HM09V) Summary

Product Description	Human CD19 VLP is expressed from HEK293. It contains Met1-Arg556 (It may have cross reaction with anti-His antibody).
Product Background	CD19 is a 95 kDa transmembrane glycoprotein that plays a central role in B cell activation and humoral immune responses. Functions as coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens. Activates signaling pathways that lead to the activation of phosphatidylinositol 3-kinase and the mobilization of intracellular Ca2 stores.
Product Category	Recombinant Protein / Antibody discovery / Multiple transmembrane proteins / VLP \| CAR-T targets \| ADC targets

Protein	CD19
Synonyms	CD19; B4; CVID3; Leu-12; MGC12802
Accession	P15391-1
Species	Human
Biotinylated	no
Amino Acid Range	Met1-Arg556
Molecular Weight	The target protein has a predicted MW of 62.04 kDa.
Activity	Immobilized Human CD19 VLP at 2 ug/ml (100ul/well) on the plate. Dose response curve for Coltuximab, hFc Tag with the EC50 of 4.9ng/ml determined by ELISA.
Fluorophore	Unconjugated
Expression System	HEK293
Purity	> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22 um filtered solution in PBS, 300mM L-arginine (pH 7.4). Notice: If you need it for immunization, water-soluble adjuvant is recommended.
Stability And Storage	Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human CD19 VLP at 2 ug/ml (100ul/well) on the plate. Dose response curve for Coltuximab, hFc Tag with the EC50 of 4.9ng/ml determined by ELISA.
	Immobilized Human CD19 VLP at 2ug/ml (100ul/well) on the plate. Dose response curve for FMC63, mFc Tag with the EC50 of 4.0/-ng/ml determined by ELISA.
	Immobilized Human CD19 VLP at 2ug/ml (100ul/well) on the plate. Dose response curve for Inebilizumab, hFc Tag with the EC50 of 4.3ng/ml determined by ELISA.
	Immobilized Human CD19 VLP at 2ug/ml (100ul/well) on the plate. Dose response curve for Denintuzumab, hFc Tag with the EC50 of 10.9ng/ml determined by ELISA.
	The purity of Human CD19 VLP is greater than 95% as determined by SEC-HPLC.

Other Available Proteins:

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