Human CD19 VLP (CD1-HM09V)
  • Express System: HEK293
  • Purity: > 95% as determined by HPLC
  • Activity: Immobilized Human CD19 VLP at 2 ug/ml (100ul/well) on the plate. Dose response curve for Coltuximab, hFc Tag with the EC50 of 4.9ng/ml determined by ELISA.
  • Amino Acid Range: Met1-Arg556
Catalog #CD1-HM09V
Regular price $1,210.00
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Human CD19 VLP (CD1-HM09V) Summary

Product Description

Human CD19 VLP is expressed from HEK293. It contains Met1-Arg556 (It may have cross reaction with anti-His antibody).

Product Background

CD19 is a 95 kDa transmembrane glycoprotein that plays a central role in B cell activation and humoral immune responses. Functions as coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens. Activates signaling pathways that lead to the activation of phosphatidylinositol 3-kinase and the mobilization of intracellular Ca2 stores.

Product Category

Recombinant Protein / Antibody discovery / Multiple transmembrane proteins / VLP | CAR-T targets | ADC targets

Human CD19 VLP (CD1-HM09V) Specifications/Details

Protein
CD19
Synonyms
CD19; B4; CVID3; Leu-12; MGC12802
Accession
Species
Human
Biotinylated
no
Amino Acid Range
Met1-Arg556
Molecular Weight
The target protein has a predicted MW of 62.04 kDa.
Activity
Immobilized Human CD19 VLP at 2 ug/ml (100ul/well) on the plate. Dose response curve for Coltuximab, hFc Tag with the EC50 of 4.9ng/ml determined by ELISA.

Fluorophore

Unconjugated
Expression System
HEK293
Purity
> 95% as determined by HPLC
Endotoxin
Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
Liquid
Shipping
Shipped with dry ice.
Formulation
Supplied as 0.22 um filtered solution in PBS, 300mM L-arginine (pH 7.4). Notice: If you need it for immunization, water-soluble adjuvant is recommended.
Stability And Storage
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Immobilized Human CD19 VLP at 2 ug/ml (100ul/well) on the plate. Dose response curve for Coltuximab, hFc Tag with the EC50 of 4.9ng/ml determined by ELISA. Immobilized Human CD19 VLP at 2 ug/ml (100ul/well) on the plate. Dose response curve for Coltuximab, hFc Tag with the EC50 of 4.9ng/ml determined by ELISA.
Immobilized Human CD19 VLP at 2ug/ml (100ul/well) on the plate. Dose response curve for FMC63, mFc Tag with the EC50 of 4.0/-ng/ml determined by ELISA. Immobilized Human CD19 VLP at 2ug/ml (100ul/well) on the plate. Dose response curve for FMC63, mFc Tag with the EC50 of 4.0/-ng/ml determined by ELISA.
Immobilized Human CD19 VLP at 2ug/ml (100ul/well) on the plate. Dose response curve for Inebilizumab, hFc Tag with the EC50 of 4.3ng/ml determined by ELISA. Immobilized Human CD19 VLP at 2ug/ml (100ul/well) on the plate. Dose response curve for Inebilizumab, hFc Tag with the EC50 of 4.3ng/ml determined by ELISA.
Immobilized Human CD19 VLP at 2ug/ml (100ul/well) on the plate. Dose response curve for Denintuzumab, hFc Tag with the EC50 of 10.9ng/ml determined by ELISA. Immobilized Human CD19 VLP at 2ug/ml (100ul/well) on the plate. Dose response curve for Denintuzumab, hFc Tag with the EC50 of 10.9ng/ml determined by ELISA.
The purity of Human CD19 VLP is greater than 95% as determined by SEC-HPLC. The purity of Human CD19 VLP is greater than 95% as determined by SEC-HPLC.
Other Available Proteins:
Finding available proteins...
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