Product Description |
Recombinant Human CD200/OX-2 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Gln31-Gly232. |
Product Background |
CD200 and its receptors are highly expressed in the lung, on epithelial cells and leukocytes, and emerging evidence links dysregulation of the CD200 pathway with asthma. Moreover, pharmacological modulation of CD200 receptors was shown to improve clinical and inflammatory outcomes of preclinical asthma models. |
Product Category |
Recombinant Protein |
Target |
CD200/OX-2 |
Synonyms |
CD200; MOX1; MOX2; My033; MRC; OX-2; OX2 |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Gln31-Gly232 |
Molecular Weight |
The protein has a predicted MW of 49.2 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result. |
Activity |
Immobilized Human CD200 R1, His Tag at 2ug/ml (100ul/Well) on the plate. Dose response curve for Human CD200, hFc Tag with the EC50 of 0.77ng/ml determined by ELISA. See testing image for detail. |
Product Tag |
C-hFc |
Express System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage |
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
|
|
Immobilized Human CD200 R1, His Tag at 2ug/ml (100ul/Well) on the plate. Dose response curve for Human CD200, hFc Tag with the EC50 of 0.77ng/ml determined by ELISA. |
|
|
Human CD200 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
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The purity of Human CD200 is greater than 95% as determined by SEC-HPLC. |
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