Human CD200 R1/CRTR2 Protein (CD2-HM2R1)
Human CD200 R1/CRTR2 Protein (CD2-HM2R1)
Human CD200 R1/CRTR2 Protein (CD2-HM2R1)
  • Express System: HEK293
  • Product Tag: C-hFc
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Human CD200, His Tag at 0.5ug/ml (100ul/Well) on the plate. Dose response curve for Human CD200 R1, hFc Tag with the EC50 21.6ng/ml determined by ELISA. See testing image for detail.
  • Amino Acid Range: Ala27-Leu266
Catalog #CD2-HM2R1
Regular price $270.00
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Product Description

Recombinant Human CD200 R1/CRTR2 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Ala27-Leu266.

Product Background

CD200Fc, a chimeric molecule including the extracellular domain of CD200 and a murine IgG2a Fc region, regulates immune responses following engagement of a cell surface receptor, CD200R, expressed on cells of the myeloid and T cell lineage. A recent report focused attention on a family of CD200Rs, but concluded that only one member used CD200 as its ligand.

Product Category

Recombinant Protein / Antibody discovery

Protein

CD200 R1/CRTR2

Synonyms

CD200R; CRTR2; MOX2R; OX2R; CD200 R1; CD200 receptor 1; HCRTR2; MOX2 receptor

Accession

Species

Human

Biotinylated

no

Amino Acid Range

Ala27-Leu266

Molecular Weight

The protein has a predicted MW of 53.7 kDa. Due to glycosylation, the protein migrates to 75-105 kDa based on Bis-Tris PAGE result.

Activity

Immobilized Human CD200, His Tag at 0.5ug/ml (100ul/Well) on the plate. Dose response curve for Human CD200 R1, hFc Tag with the EC50 21.6ng/ml determined by ELISA. See testing image for detail.

Product Tag

C-hFc

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC

Endotoxin

Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Human CD200, His Tag at 0.5ug/ml (100ul/Well) on the plate. Dose response curve for Human CD200 R1, hFc Tag with the EC50 21.6ng/ml determined by ELISA. Immobilized Human CD200, His Tag at 0.5ug/ml (100ul/Well) on the plate. Dose response curve for Human CD200 R1, hFc Tag with the EC50 21.6ng/ml determined by ELISA.
Human CD200 R1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human CD200 R1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human CD200 R1 is greater than 95% as determined by SEC-HPLC. The purity of Human CD200 R1 is greater than 95% as determined by SEC-HPLC.

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