Human CD228/MFI2 Protein (MFI-HM228) Summary
Product Description |
Recombinant Human CD228/MFI2 Protein is expressed from HEK293 with hFc (IgG1) tag tag at the C-terminus.It contains Gly20-Cys709. |
Product Background |
Melanotransferrin is typically overexpressed in melanoma cells compared to other cell types - including cancer cells - and is efficiently sorted and secreted with nanovesicles, or so-called exosomes, due to its membrane-anchoring by a glycosylphosphatidylinositol. Melanotransferrin is exposed on the surface of exosomes and is accessible for antibody recognition. |
Product Category |
Recombinant Protein / Antibody discovery / ADC targets |
Human CD228/MFI2 Protein (MFI-HM228) Specifications/Details
Protein |
CD228/MFI2 |
Synonyms |
Melanotransferrin; CD228; MFI2; MELTF; MAP97; MFI2 |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Gly20-Cys709 |
Molecular Weight |
The protein has a predicted MW of 101.45 kDa. Due to glycosylation, the protein migrates to 100-130 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-hFc (IgG1) |
Fluorophore |
Unconjugated |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 0.1 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22 um filtered solution in PBS (pH 7.4). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Other Available Proteins:
Finding available proteins...
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