Human CD229/SLAMF3 Protein (LY9-HM31D)

  • Express System: HEK293
  • Product Tag: C-mFc
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Gly251-Asn452

Catalog: LY9-HM31D

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Product Description Recombinant Human CD229/SLAMF3 Protein is expressed from HEK293 with mFc (IgG1) tag at the C-terminus.It contains Gly251-Asn452.

Product Background

CD229 was strongly and homogeneously overexpressed on the PC of patients with monoclonal gammopathy of undetermined significance (MGUS), smoldering myeloma, MM, and PC leukemia. CD229 was particularly overexpressed on those PC showing an abnormal phenotype such as expression of CD56. Most importantly, CD229 was also highly expressed on those cells in the patients' BM displaying the phenotype of chemotherapy-resistant and myeloma-propagating cells.

Product Category

Recombinant Protein

Target

CD229/SLAMF3
Accession

Species

Human

Amino Acid Range

Gly251-Asn452
Molecular Weight The protein has a predicted MW of 48.04 kDa. Due to glycosylation, the protein migrates to 55-70 kDa based on Tris-Bis PAGE result.

Product Tag

C-mFc

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Liquid
Shipping Shipped with dry ice.
Formulation Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
The purity of Human CD229 is greater than 95% as determined by SEC-HPLC.
Human CD229 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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