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Human/Cynomolgus/Rhesus macaque CD40 Ligand/TNFSF5 Protein (CDL-HE14L) Summary
Product Description |
Recombinant Human/Cynomolgus/Rhesus macaque CD40 Ligand/TNFSF5 Protein is expressed from E.coli with His tag at the C-terminus.It contains Gln114-Leu261. |
Product Background |
CD40 ligand or CD40L, also called CD154,- is a protein that is primarily expressed on activated T cells and is a member of the TNF superfamily of molecules. It binds to CD40 (protein) on antigen-presenting cells (APC), which leads to many effects depending on the target cell type. In total CD40L has three binding partners: CD40, α5β1 integrin and αIIbβ3. CD154 acts as a costimulatory molecule and is particularly important on a subset of T cells called T follicular helper cells. |
Product Category |
Recombinant Protein / Antibody discovery / Antibody discovery | Others |
Human/Cynomolgus/Rhesus macaque CD40 Ligand/TNFSF5 Protein (CDL-HE14L) Specifications/Details
Protein |
CD40 Ligand/TNFSF5 |
Synonyms |
CD40L; CD40LG; CD154; TNFSF5; TNFSF5IMD3; CD40LIGM; gp39; HIGM1; T-BAM; TRAP; IGM; IMD3; CD40 Ligand |
Accession |
|
Species |
Human/Cynomolgus/Rhesus macaque |
Biotinylated |
no |
Amino Acid Range |
Gln114-Leu261 |
Molecular Weight |
The protein has a predicted MW of 17.15 kDa same as Bis-Tris PAGE result. |
Activity |
Immobilized Human CD40, hFc Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Human/Cynomolgus/Rhesus macaque CD40 Ligand, His Tag with the EC50 of 57.6ng/ml determined by ELISA (QC Test). |
Product Tag |
C-His |
Fluorophore |
Unconjugated |
Expression System |
E.coli |
Purity |
> 95% as determined by Bis-Tris PAGE |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22 um filtered solution in PBS, 10% glycerol (pH 7.4). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Validation Images
|
|
Immobilized Human CD40, hFc Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Human/Cynomolgus/Rhesus macaque CD40 Ligand, His Tag with the EC50 of 57.6ng/ml determined by ELISA (QC Test). |
|
|
Human/Cynomolgus/Rhesus macaque CD40 Ligand on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
Other Available Proteins:
Finding available proteins...
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