Human CD40 Ligand/TNFSF5 Protein (CDL-HE14L)
  • Express System: E.coli
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE
  • Activity: Immobilized Human CD40, hFc Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Human CD40 Ligand, His Tag with the EC50 of 57.6ng/ml determined by ELISA (QC Test). See testing image for detail.
  • Amino Acid Range: Gln114-Leu261
Catalog #CDL-HE14L
Regular price $330.00
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Product Description

Recombinant Human CD40 Ligand/TNFSF5 Protein is expressed from E.coli with His tag at the C-terminus.It contains Gln114-Leu261.

Product Background

CD40 ligand or CD40L, also called CD154,- is a protein that is primarily expressed on activated T cells and is a member of the TNF superfamily of molecules. It binds to CD40 (protein) on antigen-presenting cells (APC), which leads to many effects depending on the target cell type. In total CD40L has three binding partners: CD40, α5β1 integrin and αIIbβ3. CD154 acts as a costimulatory molecule and is particularly important on a subset of T cells called T follicular helper cells.

Product Category

Recombinant Protein / Antibody discovery

Protein

CD40 Ligand/TNFSF5

Synonyms

CD40L; CD40LG; CD154; TNFSF5; TNFSF5IMD3; CD40LIGM; gp39; HIGM1; T-BAM; TRAP; IGM; IMD3; CD40 Ligand

Accession

Species

Human

Biotinylated

no

Amino Acid Range

Gln114-Leu261

Molecular Weight

The protein has a predicted MW of 17.15 kDa same as Bis-Tris PAGE result.

Activity

Immobilized Human CD40, hFc Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Human CD40 Ligand, His Tag with the EC50 of 57.6ng/ml determined by ELISA (QC Test). See testing image for detail.

Product Tag

C-His

Expression System

E.coli

Purity

> 95% as determined by Bis-Tris PAGE

Endotoxin

Less than 1EU per ug by the LAL method.
Form
Liquid
Shipping
Shipped with dry ice.
Formulation
Supplied as 0.22 um filtered solution in PBS, 10% glycerol (pH 7.4).
Stability And Storage
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Human CD40, hFc Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Human CD40 Ligand, His Tag with the EC50 of 57.6ng/ml determined by ELISA (QC Test). Immobilized Human CD40, hFc Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Human CD40 Ligand, His Tag with the EC50 of 57.6ng/ml determined by ELISA (QC Test).
Human CD40 Ligand on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human CD40 Ligand on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

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support@kactusbio.us

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