Name: Human CD40/TNFRSF5 Protein, Ultra Low Endotoxin (CD4-HM140-UL)
Brand: KactusBio
SKU: CD4-HM140-UL-100UG
Price: 236.0 USD
Availability: InStock

Human CD40/TNFRSF5 Protein, Ultra Low Endotoxin (CD4-HM140-UL)

Immobilized Human CD40, His Tag at 2ug/ml (100ul/Well) on the plate. Dose response curve for Human CD40 Ligand (Trimer) , hFc Tag with the EC50 of 79.7ng/ml determined by ELISA.

Immobilized Human CD40, His Tag at 1ug/ml (100ul/Well). Dose response curve for Anti-CD40 Antibody, hFc Tag with the EC50 of 16.8ng/ml determined by ELISA.

Human CD40 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Human CD40 is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Human CD40, His Tag at 2ug/ml (100ul/Well) on the plate. Dose response curve for Human CD40 Ligand (Trimer) , hFc Tag with the EC50 of 79.7ng/ml determined by ELISA. See testing image for detail.
Amino Acid Range: Glu21-Arg193

Catalog #CD4-HM140-UL

Size

100UG

500UG

Order now, ships by:

[{"id":47049777578206,"title":"100UG","option1":"100UG","option2":null,"option3":null,"sku":"CD4-HM140-UL-100UG","requires_shipping":true,"taxable":true,"featured_image":null,"available":true,"name":"Human CD40\/TNFRSF5 Protein, Ultra Low Endotoxin (CD4-HM140-UL) - 100UG","public_title":"100UG","options":["100UG"],"price":23600,"weight":5,"compare_at_price":null,"inventory_management":"shopify","barcode":null,"requires_selling_plan":false,"selling_plan_allocations":[],"quantity_rule":{"min":1,"max":null,"increment":1}},{"id":47049895313630,"title":"500UG","option1":"500UG","option2":null,"option3":null,"sku":"CD4-HM140-UL-500UG","requires_shipping":true,"taxable":true,"featured_image":null,"available":true,"name":"Human CD40\/TNFRSF5 Protein, Ultra Low Endotoxin (CD4-HM140-UL) - 500UG","public_title":"500UG","options":["500UG"],"price":78700,"weight":5,"compare_at_price":null,"inventory_management":"shopify","barcode":null,"requires_selling_plan":false,"selling_plan_allocations":[],"quantity_rule":{"min":1,"max":null,"increment":1}}]

Product Description	Recombinant Human CD40/TNFRSF5 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu21-Arg193.
Product Background	CD40 is a costimulatory protein found on antigen presenting cells and is required for their activation. The binding of CD154 (CD40L) on TH cells to CD40 activates antigen presenting cells and induces a variety of downstream effects.CD40 molecule is a potential target for cancer immunotherapy. There are number of completed and ongoing clinical trials where agonistic anti-CD40 monoclonal antibodies are employed to activate an anti-tumor T cell response via activation of dendritic cells.
Product Category	Recombinant Protein / Antibody discovery / Immune checkpoint proteins

Protein	CD40/TNFRSF5
Synonyms	CD40; CD40L receptor;- TNFRSF5; CD40 antigen; CD40 molecule; CDw40; MGC9013;
Accession	P25942-1
Species	Human
Biotinylated	no
Amino Acid Range	Glu21-Arg193
Molecular Weight	The protein has a predicted MW of 20 kDa. Due to glycosylation, the protein migrates to 35-40 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human CD40, His Tag at 2ug/ml (100ul/Well) on the plate. Dose response curve for Human CD40 Ligand (Trimer) , hFc Tag with the EC50 of 79.7ng/ml determined by ELISA. See testing image for detail.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 0.01 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human CD40, His Tag at 2ug/ml (100ul/Well) on the plate. Dose response curve for Human CD40 Ligand (Trimer) , hFc Tag with the EC50 of 79.7ng/ml determined by ELISA.
	Immobilized Human CD40, His Tag at 1ug/ml (100ul/Well). Dose response curve for Anti-CD40 Antibody, hFc Tag with the EC50 of 16.8ng/ml determined by ELISA.
	Human CD40 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human CD40 is greater than 95% as determined by SEC-HPLC.