Name: Human CD44 Protein (CDX-HM244)
Brand: KactusBio
SKU: CDX-HM244-100UG
Price: 225.0 USD
Availability: InStock

Express System: HEK293
Product Tag: C-hFc
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Human CD44, hFc Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Biotinylated Anti-CD44 Antibody, hFc Tag with the EC50 of 28.7ng/ml determined by ELISA (QC Test). See testing image for detail.
Amino Acid Range: Gln21-Pro220 & Gln386-Ala427

Catalog #CDX-HM244

Size

100UG

500UG

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Product Description	Recombinant Human CD44 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Gln21-Pro220 & Gln386-Ala427.
Product Background	CD44 is a hyaluronan binding cell surface signal transducing receptor that influences motility, cell survival and proliferation as well as the formation of tumor microenvironment. CD44 contains two variable regions encoded by variable exons. Alternative splicing, which is often deregulated in cancer, can produce various isoforms of CD44 with properties that may have different tissue specific effects and therefore even diverse effects on cancer progression
Product Category	Recombinant Protein / Antibody discovery

Protein	CD44
Synonyms	CD44; CDw44; Epican; ECMR-III; LHR; MDU2; MDU3; MIC4; PGP-I; CSPG8; HCELL; HUTCH-I; IN; MC56
Accession	P16070-1
Species	Human
Biotinylated	no
Amino Acid Range	Gln21-Pro220 & Gln386-Ala427
Molecular Weight	The protein has a predicted MW of 53.57 kDa. Due to glycosylation, the protein migrates to 70-100 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human CD44, hFc Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Biotinylated Anti-CD44 Antibody, hFc Tag with the EC50 of 28.7ng/ml determined by ELISA (QC Test). See testing image for detail.
Product Tag	C-hFc
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human CD44, hFc Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Biotinylated Anti-CD44 Antibody, hFc Tag with the EC50 of 28.7ng/ml determined by ELISA (QC Test).
	Human CD44 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human CD44 is greater than 95% as determined by SEC-HPLC.