• Express System: HEK293
  • Product Tag: C-hFc (IgG1)
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Human CD44v9, hFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-CD44v9 Antibody, hFc Avi Tag with the EC50 of 13.1ng/ml determined by ELISA.
  • Amino Acid Range: Gln21-Pro220 & Gly506-Ser534
Catalog #CDX-HM2V9
Price
Regular price $345.00
Regular price Sale price $345.00
/
Size
Avantor VWR Fisher Scientific

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Human CD44v9 Protein (CDX-HM2V9) Summary

Product Description

 Recombinant Human CD44v9 Protein is expressed from HEK293 with hFc (IgG1) tag at the C-terminus.It contains Gln21-Pro220 & Gly506-Ser534.

Product Background

 CD44 is a hyaluronan binding cell surface signal transducing receptor that influences motility, cell survival and proliferation as well as the formation of tumor microenvironment. CD44 contains two variable regions encoded by variable exons. Alternative splicing, which is often deregulated in cancer, can produce various isoforms of CD44 with properties that may have different tissue specific effects and therefore even diverse effects on cancer progression

Product Category

 Recombinant Protein / Antibody discovery / ADC targets

Human CD44v9 Protein (CDX-HM2V9) Specifications/Details

Protein
 CD44
Synonyms
 CD44; CDw44; Epican; ECMR-III; LHR; MDU2; MDU3; MIC4; PGP-I; CSPG8; HCELL; HUTCH-I; IN; MC56
Accession
Species
 Human
Biotinylated
 no
Amino Acid Range
 Gln21-Pro220 & Gly506-Ser534
Molecular Weight
 The protein has a predicted MW of 51.17 kDa. Due to glycosylation, the protein migrates to 80-100 kDa based on Bis-Tris PAGE result.
Activity
 Immobilized Human CD44v9, hFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-CD44v9 Antibody, hFc Avi Tag with the EC50 of 13.1ng/ml determined by ELISA.
Product Tag
 C-hFc (IgG1)

Fluorophore

 Unconjugated
Expression System
 HEK293
Purity
 > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
 Less than 0.1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
 Liquid
Shipping
 Shipped with dry ice.
Formulation
 Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage
 Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Immobilized Human CD44v9, hFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-CD44v9 Antibody, hFc Avi Tag with the EC50 of 13.1ng/ml determined by ELISA. Immobilized Human CD44v9, hFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-CD44v9 Antibody, hFc Avi Tag with the EC50 of 13.1ng/ml determined by ELISA.
Human CD44v9 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human CD44v9 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human CD44v9 is greater than 95% as determined by SEC-HPLC. The purity of Human CD44v9 is greater than 95% as determined by SEC-HPLC.
Other Available Proteins:
Finding available proteins...
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