Human CD52 Protein (CD5-HM352)
Catalog: CD5-HM352
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| Product Description | Recombinant Human CD52 Protein is expressed from HEK293 with mFc (IgG1) tag at the C-Terminus.It contains Gly25-Ser36. |
Product Background |
CD52, also known as CAMPATH-1 antigen, HE5, and gp20, is a cell surface glycoprotein that can be targeted to induce immune suppression by complement-mediated cell lysis. Mature human CD52 is a 12 amino acid peptide that is tethered to the cell surface with a GPI linkage.CD52 may play a role in carrying and orienting carbohydrate, as well as having a more specific role. |
Product Category |
Recombinant Protein |
Target |
CD52 |
| Synonyms | CD52 molecule; CD52; CDW52 antigen (CAMPATH-1 antigen); CDw52; He5; HEL-S-171mP |
Gene/Protein ID |
P31358 |
Species |
Human |
Exact Sequence |
Gly25-Ser36 |
| Molecular Weight | The protein has a predicted MW of 27.6 kDa. Due to glycosylation, the protein migrates to 38-48 kDa based on Tris-Bis PAGE result. |
Product Tag |
C-mFc |
Express System |
HEK293 |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per ug by the LAL method. |
| Form | Lyophilized |
| Shipping | Shipped at ambient temperature. |
| Formulation | Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Stability And Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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The purity of-Human CD52 is greater than 95% as determined by SEC-HPLC. |
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Human CD52 on Tris-Bis PAGE under reduced conditions. The purity is greater than 95%. |
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