Name: Human CD8 alpha/CD8A Protein (CD8-HM18A)
Brand: KactusBio
SKU: CD8-HM18A-100UG
Price: 345.0 USD
Availability: InStock

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE
Activity: Immobilized Human CD8 alpha, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-CD8 Antibody, hFc Tag with the EC50 of 16.9ng/ml determined by ELISA (QC Test). See testing image for detail.
Amino Acid Range: Ser22-Asp182

Catalog #CD8-HM18A

Size

100UG

500UG

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Product Description	Recombinant Human CD8 alpha/CD8A Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ser22-Asp182.
Product Background	CD8 alpha enhances the responses of antigen-specific CTL activated through TCR through binding MHC class I, favoring lipid raft partitioning of TCR, and inducing intracellular signaling. CD8 alpha is also found on dendritic cells and rat macrophages, but whether CD8 alpha enhances responses of a partner receptor, like TCR, to activate these cells is not known.
Product Category	Recombinant Protein / Antibody discovery / CAR-T targets

Protein	CD8 alpha/CD8A
Synonyms	CD8a; Lyt-2; CD8; Leu2; MAL; p32; CD8a molecule; OKT8 T-cell antigen
Accession	P01732-1
Species	Human
Biotinylated	no
Amino Acid Range	Ser22-Asp182
Molecular Weight	The protein has a predicted MW of 18.70 kDa. Due to glycosylation, the protein migrates to 28-35 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human CD8 alpha, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-CD8 Antibody, hFc Tag with the EC50 of 16.9ng/ml determined by ELISA (QC Test). See testing image for detail.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human CD8 alpha, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-CD8 Antibody, hFc Tag with the EC50 of 16.9ng/ml determined by ELISA (QC Test).
	Human CD8 alpha on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.