Name: Human CD8 alpha/CD8A Protein (CD8-HM28A)
Brand: KactusBio
SKU: CD8-HM28A-100UG
Price: 375.0 USD
Availability: InStock

Express System: HEK293
Product Tag: C-hFc (IgG1)
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Human CD8 alpha, hFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-CD8 Antibody, hFc Tag with the EC50 of 9.2ng/ml determined by ELISA.
Amino Acid Range: Ser22-Asp182

Catalog #CD8-HM28A

Size

100UG

500UG

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Human CD8 alpha/CD8A Protein (CD8-HM28A) Summary

Product Description	Recombinant Human CD8 alpha/CD8A Protein is expressed from HEK293 with hFc (IgG1) tag at the C-terminus.It contains Ser22-Asp182.
Product Background	CD8 alpha enhances the responses of antigen-specific CTL activated through TCR through binding MHC class I, favoring lipid raft partitioning of TCR, and inducing intracellular signaling. CD8 alpha is also found on dendritic cells and rat macrophages, but whether CD8 alpha enhances responses of a partner receptor, like TCR, to activate these cells is not known.
Product Category	Recombinant Protein / Antibody discovery / CAR-T targets

Human CD8 alpha/CD8A Protein (CD8-HM28A) Specifications/Details

Protein	CD8 alpha/CD8A
Synonyms	CD8a; Lyt-2; CD8; Leu2; MAL; p32; CD8a molecule; OKT8 T-cell antigen
Accession	P01732-1
Species	Human
Biotinylated	no
Amino Acid Range	Ser22-Asp182
Molecular Weight	The protein has a predicted MW of 43.55 kDa. Due to glycosylation, the protein migrates to 53-63 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human CD8 alpha, hFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-CD8 Antibody, hFc Tag with the EC50 of 9.2ng/ml determined by ELISA.
Product Tag	C-hFc (IgG1)
Fluorophore	Unconjugated
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 0.1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human CD8 alpha, hFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-CD8 Antibody, hFc Tag with the EC50 of 9.2ng/ml determined by ELISA.
	Human CD8 alpha on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human CD8 alpha is greater than 95% as determined by SEC-HPLC.

Other Available Proteins:

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