Human CD93/C1q R1 Protein (CD9-HM293)

  • Express System: HEK293
  • Product Tag: C-hFc
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Human IGFBP-7, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human CD93, hFc Tag with the EC50 of 1.10ug/ml determined by ELISA. See testing image for detail.
  • Exact Sequence: Thr22-Lys580

Catalog: CD9-HM293

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Product Description Recombinant Human CD93/C1q R1 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Thr22-Lys580.

Product Background

CD93 has been shown critical roles in inflammatory and immune diseases. CD93 silencing increased IL-6 and TSLP, but not IL-33 levels in culture supernatants. HDM-induced asthma mice showed significant airway hyperresponsiveness and inflammation with Th2 cytokine activation, along with decreased CD93 expression in bronchial epithelial cells and lung homogenates but increased serum CD93 levels.

Product Category

Recombinant Protein

Target

CD93/C1q R1
Synonyms C1q/MBL/SPA receptor; C1qR; C1qR(p); C1qRp; CDw93; CD93; C1QR1; MXRA4; ECSM3; dJ737E23.1

Gene/Protein ID

Q9NPY3

Species

Human

Exact Sequence

Thr22-Lys580
Molecular Weight The protein has a predicted MW of 85 kDa. Due to glycosylation, the protein migrates to 115-120 kDa based on Tris-Bis PAGE result.

Activity

Immobilized Human IGFBP-7, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human CD93, hFc Tag with the EC50 of 1.10ug/ml determined by ELISA. See testing image for detail.

Product Tag

C-hFc

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Immobilized Human IGFBP-7, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human CD93, hFc Tag with the EC50 of 1.10ug/ml determined by ELISA.
The purity of Human CD93 is greater than 95% as determined by SEC-HPLC.
Human CD93 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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