Name: Human CD96/TACTILE (C110S) Protein (CD9-HM19S)
Brand: KactusBio
SKU: CD9-HM19S-100UG
Price: 346.5 USD
Availability: InStock

Human CD96/TACTILE (C110S) Protein (CD9-HM19S)

Human CD155, hFc Tag captured on CM5 Chip via Protein A can bind Human CD96 (C110S), His Tag with an affinity constant of 0.289 uM as determined in SPR assay (Biacore T200).

Immobilized Anti-CD96 Antibody, hFc Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Human CD96 (C110S), His Tag with the EC50 of 28.7ng/ml determined by ELISA (QC test).

Human CD96 (C110S) on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Human CD96 (C110S) is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Anti-CD96 Antibody, hFc Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Human CD96 (C110S), His Tag with the EC50 of 28.7ng/ml determined by ELISA (QC test). The affinity constant of 0.289 uM as determined in SPR assay (Biacore T200). See testing image for detail.
Amino Acid Range: Val22-Met503(C110S)

Catalog #CD9-HM19S

Size

100UG

500UG

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Product Description	Recombinant Human CD96/TACTILE (C110S) Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Val22-Met503(C110S).
Product Background	The receptors CD96 and TIGIT are expressed on the surface of T and natural killer (NK) cells, and recent studies suggest both play important inhibitory roles in immune function. CD96 has been shown to modulate immune cell activity in mice, with Cd96-/- mice displaying hypersensitive NK-cell responses to immune challenge and significant tumor resistance. The counterbalance between the putative inhibitory CD96 and TIGIT receptors and the activating receptor, CD226, offers unique strategies for immuno-oncology drug development.
Product Category	Recombinant Protein / Antibody discovery / Immune checkpoint proteins

Protein	CD96/TACTILE (C110S)
Synonyms	CD96 molecule; CD96; DKFZp667E2122; TACTILE
Accession	P40200-2
Species	Human
Biotinylated	no
Amino Acid Range	Val22-Met503(C110S)
Molecular Weight	The protein has a predicted MW of 54.63 kDa. Due to glycosylation, the protein migrates to 100-130 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Anti-CD96 Antibody, hFc Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Human CD96 (C110S), His Tag with the EC50 of 28.7ng/ml determined by ELISA (QC test). The affinity constant of 0.289 uM as determined in SPR assay (Biacore T200). See testing image for detail.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Human CD155, hFc Tag captured on CM5 Chip via Protein A can bind Human CD96 (C110S), His Tag with an affinity constant of 0.289 uM as determined in SPR assay (Biacore T200).
	Immobilized Anti-CD96 Antibody, hFc Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Human CD96 (C110S), His Tag with the EC50 of 28.7ng/ml determined by ELISA (QC test).
	Human CD96 (C110S) on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human CD96 (C110S) is greater than 95% as determined by SEC-HPLC.