Name: Human CD98 Protein (CD9-HM198)
Brand: KactusBio
SKU: CD9-HM198-100UG
Price: 247.5 USD
Availability: InStock

Express System: HEK293
Product Tag: N-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Human CD98, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-CD98 Antibody, hFc Tag with the EC50 of 14.2ng/ml determined by ELISA.
Amino Acid Range: Arg206-Ala630
Other Available Proteins:

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Catalog #CD9-HM198

Size

100UG

500UG

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Human CD98 Protein (CD9-HM198) Summary

Product Description	Recombinant Human CD98 Protein is expressed from HEK293 with His tag at the N-Terminus.It contains Arg206-Ala630.
Product Background	The type II transmembrane protein CD98, best known as the heavy chain of the heterodimeric amino acid transporters (HAT), is required for the surface expression and basolateral localization of this transporter complex in polarized epithelial cells. CD98 also interacts with beta1 integrins resulting in an increase in their affinity for ligand. In this study we explored the role of the transmembrane and cytoplasmic domains of CD98 on integrin-dependent cell adhesion and migration in polarized renal epithelial cells.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Human CD98 Protein (CD9-HM198) Specifications/Details

Protein	CD98
Synonyms	4F2hc; CD98; SLC3A2; 4F2; CD98HC; MDU1; NACAE; 4T2HC
Accession	AAH01061
Species	Human
Biotinylated	no
Amino Acid Range	Arg206-Ala630
Molecular Weight	The protein has a predicted MW of 47.9 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human CD98, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-CD98 Antibody, hFc Tag with the EC50 of 14.2ng/ml determined by ELISA.
Product Tag	N-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human CD98, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-CD98 Antibody, hFc Tag with the EC50 of 14.2ng/ml determined by ELISA.
	Human CD98 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	Loaded Anti-CD98 Ab., hFc-Avi Tag on ProA-Biosensor can bind Human CD98, His Tag with an affinity constant of 7.21 nM as determined in BLI assay (Gator® Prime).
	The purity of Human CD98 is greater than 95% as determined by SEC-HPLC.