Name: Human CDCP1 CTF Protein (CDC-HM20C)
Brand: KactusBio
SKU: CDC-HM20C-100UG
Price: 450.0 USD
Availability: InStock

Express System: HEK293
Product Tag: C-hFc (IgG1)
Purity: > 90% as determined by Bis-Tris PAGE;> 90% as determined by HPLC
Activity: The affinity constant of 59.11 nM as determined in SPR assay (Biacore T200).
Amino Acid Range: Lys369-Thr667

Catalog #CDC-HM20C

Size

100UG

500UG

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Human CDCP1 CTF Protein (CDC-HM20C) Summary

Product Description	Recombinant Human CDCP1 CTF Protein is expressed from HEK293 with hFc (IgG1) tag at the C-terminus.It contains Lys369-Thr667.
Product Background	Tumor metastasis depends on the dynamic regulation of cell adhesion through β1-integrin. The Cub-Domain Containing Protein-1, CDCP1, is a transmembrane glycoprotein which regulates cell adhesion. Overexpression and loss of CDCP1 have been observed in the same cancer types to promote metastatic progression.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery/Others

Human CDCP1 CTF Protein (CDC-HM20C) Specifications/Details

Protein	CDCP1
Synonyms	CDCP1; CD318; SIMA135; TRASK; UNQ2486; PRO5773
Accession	Q9H5V8-1
Species	Human
Biotinylated	no
Amino Acid Range	Lys369-Thr667
Molecular Weight	The protein has a predicted MW of 59.85 kDa. Due to glycosylation, the protein migrates to 75-95 kDa based on Bis-Tris PAGE result.
Activity	The affinity constant of 59.11 nM as determined in SPR assay (Biacore T200).
Product Tag	C-hFc (IgG1)
Fluorophore	Unconjugated
Expression System	HEK293
Purity	> 90% as determined by Bis-Tris PAGE;> 90% as determined by HPLC
Endotoxin	Less than 0.1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Human CDCP1 CTF, hFc Tag immobilized on CM5 Chip can bind Anti-CDCP1 CTF Antibody1 with an affinity constant of 59.11 nM as determined in SPR assay (Biacore T200).
	Human CDCP1 CTF, hFc Tag immobilized on CM5 Chip can bind Anti-CDCP1 CTF Antibody2 with an affinity constant of 153.23 nM as determined in SPR assay (Biacore T200).
	Human CDCP1 CTF on Bis-Tris PAGE under reduced condition. The purity is greater than 90%.
	The purity of Human CDCP1 CTF is greater than 90% as determined by SEC-HPLC.

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