• Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 85% as determined by HPLC
  • Amino Acid Range: Gly54-Thr617
Catalog #CDH-HM111
Price
Regular price $34650
Regular price Sale price $34650
/
Size
Avantor VWR Fisher Scientific

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Human CDH11/Cadherin 11 Protein (CDH-HM111) Summary

Product Description

Recombinant Human CDH11/Cadherin 11 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gly54-Thr617.

Product Background

CDH11 belongs to a group of transmembrane proteins that are principally located in adherens junctions. CDH11 mediates homophilic cell-to-cell adhesion, which may promote the development of cirrhosis. CDH11 expression was positively correlated with liver fibrosis in patients with cirrhosis, and could therefore be a prognostic factor in patients with liver fibrosis.

Human CDH11/Cadherin 11 Protein (CDH-HM111) Specifications/Details

Protein
CDH11/Cadherin 11
Synonyms
Cadherin-11;OSF-4;Osteoblast cadherin;OB-cadherin;CDH11;CAD11OSF-4; CDHOB;OB;OSF4; CAD11OSF4
Accession
Species
Human
Biotinylated
no
Amino Acid Range
Gly54-Thr617
Molecular Weight
The protein has a predicted MW of 66.32 kDa. Due to glycosylation, the protein migrates to 67-70 kDa based on Bis-Tris PAGE result.
Product Tag
C-His
Fluorophore
Unconjugated
Expression System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 85% as determined by HPLC
Endotoxin
Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
-20 to -80ยฐC for 12 months as supplied from date of receipt.๏ผ›-80ยฐC for 3 months after reconstitution.๏ผ›Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Human CDH11 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human CDH11 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human CDH11 is greater than 85% as determined by SEC-HPLC. The purity of Human CDH11 is greater than 85% as determined by SEC-HPLC.
Other Available Proteins:
Finding available proteins...