Product Description |
Recombinant Human CDH11/Cadherin 11 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gly54-Thr617. |
Product Background |
CDH11 belongs to a group of transmembrane proteins that are principally located in adherens junctions. CDH11 mediates homophilic cell-to-cell adhesion, which may promote the development of cirrhosis. CDH11 expression was positively correlated with liver fibrosis in patients with cirrhosis, and could therefore be a prognostic factor in patients with liver fibrosis. |
Product Category |
Recombinant Protein |
Target |
CDH11/Cadherin 11 |
Synonyms |
Cadherin-11；OSF-4；Osteoblast cadherin；OB-cadherin；CDH11；CAD11OSF-4； CDHOB；OB |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Gly54-Thr617 |
Molecular Weight |
The protein has a predicted MW of 66.32 kDa. Due to glycosylation, the protein migrates to 67-70 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-His |
Express System |
HEK293 |
Purity |
> 90% as determined by Bis-Tris PAGE |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage |
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
|
|
Human CDH11 on Bis-Tris PAGE under reduced condition. The purity is greater than 90%. |
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