Human CDH11/Cadherin 11 Protein (CDH-HM111) Summary
Product Description |
Recombinant Human CDH11/Cadherin 11 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gly54-Thr617. |
Product Background |
CDH11 belongs to a group of transmembrane proteins that are principally located in adherens junctions. CDH11 mediates homophilic cell-to-cell adhesion, which may promote the development of cirrhosis. CDH11 expression was positively correlated with liver fibrosis in patients with cirrhosis, and could therefore be a prognostic factor in patients with liver fibrosis. |
Product Category |
Recombinant Protein / Antibody discovery / Antibody discovery | Others |
Human CDH11/Cadherin 11 Protein (CDH-HM111) Specifications/Details
Protein |
CDH11/Cadherin 11 |
Synonyms |
Cadherin-11;OSF-4;Osteoblast cadherin;OB-cadherin;CDH11;CAD11OSF-4; CDHOB;OB |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Gly54-Thr617 |
Molecular Weight |
The protein has a predicted MW of 66.32 kDa. Due to glycosylation, the protein migrates to 67-70 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-His |
Expression System |
HEK293 |
Purity |
> 90% as determined by Bis-Tris PAGE |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
Stability And Storage |
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
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