Human CDH17/Cadherin 17 Domain 3&4 Protein (CDH-HM3D3)
Human CDH17/Cadherin 17 Domain 3&4 Protein (CDH-HM3D3)
Human CDH17/Cadherin 17 Domain 3&4 Protein (CDH-HM3D3)
Human CDH17/Cadherin 17 Domain 3&4 Protein (CDH-HM3D3)
  • Express System: HEK293
  • Product Tag: C-mFc
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Val245-Phe449
Catalog #CDH-HM3D3
/
Size

Order now, ships by:

Product Description
 Recombinant Human CDH17/Cadherin 17 Domain 3&4 Protein is expressed from HEK293 with mFc (IgG1) tag at the C-Terminus.It contains Val245-Phe449.
Product Background
 Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.
Product Category
 Recombinant Protein
Target
 CDH17/Cadherin 17 Domain 3&4
Synonyms
 Cadherin-17; BILL-cadherin; LI-cadherin; P130; Cdh17; CDH16; HPT-1; cadherin-16;
Accession
Species
 Human
Biotinylated
 no
Amino Acid Range
 Val245-Phe449
Molecular Weight
 The protein has a predicted MW of 49.16 kDa. Due to glycosylation, the protein migrates to 55-70 kDa based on Bis-Tris PAGE result.
Product Tag
 C-mFc
Express System
 HEK293
Purity
 > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
 Less than 1EU per ug by the LAL method.
Form
 Lyophilized
Shipping
 Shipped at ambient temperature.
Formulation
 Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
 Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
 Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Human CDH17 Domain 3&4 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human CDH17 Domain 3&4 is greater than 95% as determined by SEC-HPLC.

Have more questions?

Check out our Frequently Asked Questions page for more details about product specifications, ordering, and shipments.

Contact Us

support@kactusbio.us

Recently viewed