Name: Human CDH17/Cadherin 17 Domain 6-7 Protein (CDH-HM2D2)
Brand: KactusBio
SKU: CDH-HM2D2-100UG
Price: 429.0 USD
Availability: InStock

Human CDH17/Cadherin 17 Domain 6-7 Protein (CDH-HM2D2)

Human CDH17 Domain 6-7 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Human CDH17 Domain 6-7 is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-hFc
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Amino Acid Range: Ser567-Gly777

Catalog #CDH-HM2D2

Size

100UG

500UG

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Product Description	Recombinant Human CDH17/Cadherin 17 Domain 6-7 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Ser567-Gly777.
Product Background	Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Protein	CDH17/Cadherin 17
Synonyms	Cadherin-17; BILL-cadherin; LI-cadherin; P130; Cdh17; CDH16; HPT-1; cadherin-16; FLJ26931; MGC138218; MGC142024
Accession	Q12864
Species	Human
Biotinylated	no
Amino Acid Range	Ser567-Gly777
Molecular Weight	The protein has a predicted MW of 49.29 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Bis-Tris PAGE result.
Product Tag	C-hFc
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in 20mM Tris, 150mM NaCl (pH 8.0). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Human CDH17 Domain 6-7 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human CDH17 Domain 6-7 is greater than 95% as determined by SEC-HPLC.