Human CDH17/Cadherin 17 Domain 6-7 Protein (CDH-HM2D2)

  • Express System: HEK293
  • Product Tag: C-hFc
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Exact Sequence: Ser567-Gly777

Catalog: CDH-HM2D2


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Product Description Recombinant Human CDH17/Cadherin 17 Domain 6-7 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Ser567-Gly777.

Product Background

Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.

Product Category

Recombinant Protein


CDH17/Cadherin 17 Domain 6-7

Gene/Protein ID




Exact Sequence

Molecular Weight The protein has a predicted MW of 49.29 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Tris-Bis PAGE result.

Product Tag


Express System

Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22um filtered solution in 20mM Tris, 150mM NaCl (pH 8.0). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
The purity of Human CDH17 Domain 6-7 is greater than 95% as determined by SEC-HPLC.
Human CDH17 Domain 6-7 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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