Name: Human CDH17/Cadherin 17 Domain 6-7 Protein (CDH-HM2D2)
Brand: KactusBio
SKU: CDH-HM2D2-100UG
Price: 390.0 USD
Availability: InStock

Human CDH17/Cadherin 17 Domain 6-7 Protein (CDH-HM2D2)

Express System: HEK293
Product Tag: C-hFc
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Amino Acid Range: Ser567-Gly777

Catalog #CDH-HM2D2

Size

100UG

500UG

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Product Description	Recombinant Human CDH17/Cadherin 17 Domain 6-7 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Ser567-Gly777.
Product Background	Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.
Product Category	Recombinant Protein

Target	CDH17/Cadherin 17 Domain 6-7
Accession	Q12864
Species	Human
Biotinylated	no
Amino Acid Range	Ser567-Gly777
Molecular Weight	The protein has a predicted MW of 49.29 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Bis-Tris PAGE result.
Product Tag	C-hFc
Express System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in 20mM Tris, 150mM NaCl (pH 8.0). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

	Human CDH17 Domain 6-7 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human CDH17 Domain 6-7 is greater than 95% as determined by SEC-HPLC.

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