Human CDH17/Cadherin 17 Domain 6-7 Protein (CDH-HM3D2)
Human CDH17/Cadherin 17 Domain 6-7 Protein (CDH-HM3D2)
  • Express System: HEK293
  • Product Tag: C-mFc
  • Purity: >95% as determined by Bis-Tris PAGE;>90% as determined by HPLC
  • Amino Acid Range: Ser567-Gly777
Catalog #CDH-HM3D2
Regular price $390.00
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Product Description
Recombinant Human CDH17/Cadherin 17 Domain 6-7 Protein is expressed from HEK293 with mFc tag at the C-Terminus.It contains Ser567-Gly777.
Product Background
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades. In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.
Product Category
Recombinant Protein
Target
CDH17/Cadherin 17 Domain 6-7
Accession
Species
Human
Biotinylated
no
Amino Acid Range
Ser567-Gly777
Molecular Weight
The protein has a predicted MW of 50.18 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Bis-Tris PAGE result.
Product Tag
C-mFc
Express System
HEK293
Purity
>95% as determined by Bis-Tris PAGE;>90% as determined by HPLC
Endotoxin
Less than 1 EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Human CDH17 Domain 6-7 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human CDH17 Domain 6-7 is greater than 90% as determined by SEC-HPLC.

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