Human CDH17/Cadherin 17 Domain 6 Protein (CDH-HM36D)
  • Express System: HEK293
  • Product Tag: C-mFc
  • Purity: >95% as determined by Bis-Tris PAGE;>95% as determined by HPLC
  • Amino Acid Range: Ser567-Leu667
Catalog #CDH-HM36D
Regular price $1,300.00
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Product Description
Recombinant Human CDH17/Cadherin 17 Domain 6 Protein is expressed from HEK293 with mFc (IgG2a) tag at the C-terminus.It contains Ser567-Leu667.
Product Background
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.
Product Category
Recombinant Protein
Target
CDH17/Cadherin 17 Domain 6
Synonyms
Cadherin-17; BILL-cadherin; LI-cadherin; P130; Cdh17; CDH16; HPT-1;
Accession
Species
Human
Biotinylated
no
Amino Acid Range
Ser567-Leu667
Molecular Weight
The protein has a predicted MW of 37.24 kDa. Due to glycosylation, the protein migrates to 45-55 kDa based on Bis-Tris PAGE result.
Product Tag
C-mFc
Express System
HEK293
Purity
>95% as determined by Bis-Tris PAGE;>95% as determined by HPLC
Endotoxin
Less than 0.1EU per ug by the LAL method.
Form
Liquid
Shipping
Shipped with dry ice.
Formulation
Supplied as 0.22 um filtered solution in PBS, 200mM L-arginine (pH 7.4).
Stability And Storage
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Human CDH17 Domain 6 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human CDH17 Domain 6 is greater than 95% as determined by SEC-HPLC.

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