Human CDH17/Cadherin 17 Domain 7 Protein (CDH-HM2D3)
  • Express System: HEK293
  • Product Tag: C-hFc
  • Purity: > 95% as determined by Bis-Tris PAGE
  • Amino Acid Range: Ala668-Gly777
Catalog #CDH-HM2D3
Regular price $390.00
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Product Description
Recombinant Human CDH17/Cadherin 17 Domain 7 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Ala668-Gly777.
Product Background
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.
Product Category
Recombinant Protein
Target
CDH17/Cadherin 17 Domain 7
Accession
Species
Human
Biotinylated
no
Amino Acid Range
Ala668-Gly777
Molecular Weight
The protein has a predicted MW of 38.42 kDa. Due to glycosylation, the protein migrates to 48-52 kDa based on Bis-Tris PAGE result.
Product Tag
C-hFc
Express System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE
Endotoxin
Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22 um filtered solution in 20mM Tris, 150mM NaCl (pH 8.0). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Human CDH17 Domain 7 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

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