Name: Human CDH17/Cadherin 17 Protein, Ultra Low Endotoxin (CDH-HM117-UL)
Brand: KactusBio
SKU: CDH-HM117-UL-100UG
Price: 363.0 USD
Availability: InStock

Human CDH17/Cadherin 17 Protein, Ultra Low Endotoxin (CDH-HM117-UL)

Immobilized Human CDH17, His Tag at 1 ug/ml (100 ul/Well) on the plate. Dose response curve for Anti-CDH17 Antibody, hFc Tag with the EC50 of 4.1 ng/ml determined by ELISA.

Human CDH17 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

Loaded Anti-CDH17 Ab., hFc Tag on ProA-Biosensor can bind Human CDH17, His Tag with an affinity constant of 2.26 nM as determined in BLI assay (Gator® Prime).

The purity of Human CDH17 is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Human CDH17, His Tag at 1 ug/ml (100 ul/Well) on the plate. Dose response curve for Anti-CDH17 Antibody, hFc Tag with the EC50 of 4.1 ng/ml determined by ELISA. See testing image for detail.
Amino Acid Range: Gln23-Met787

Catalog #CDH-HM117-UL

Size

100UG

500UG

Order now, ships by:

[{"id":47049778331870,"title":"100UG","option1":"100UG","option2":null,"option3":null,"sku":"CDH-HM117-UL-100UG","requires_shipping":true,"taxable":true,"featured_image":null,"available":true,"name":"Human CDH17\/Cadherin 17 Protein, Ultra Low Endotoxin (CDH-HM117-UL) - 100UG","public_title":"100UG","options":["100UG"],"price":36300,"weight":5,"compare_at_price":null,"inventory_management":"shopify","barcode":null,"requires_selling_plan":false,"selling_plan_allocations":[],"quantity_rule":{"min":1,"max":null,"increment":1}},{"id":47049896067294,"title":"500UG","option1":"500UG","option2":null,"option3":null,"sku":"CDH-HM117-UL-500UG","requires_shipping":true,"taxable":true,"featured_image":null,"available":true,"name":"Human CDH17\/Cadherin 17 Protein, Ultra Low Endotoxin (CDH-HM117-UL) - 500UG","public_title":"500UG","options":["500UG"],"price":121000,"weight":5,"compare_at_price":null,"inventory_management":"shopify","barcode":null,"requires_selling_plan":false,"selling_plan_allocations":[],"quantity_rule":{"min":1,"max":null,"increment":1}}]

Product Description	Recombinant Human CDH17/Cadherin 17 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Gln23-Met787.
Product Background	Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades. In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Protein	CDH17/Cadherin 17
Synonyms	Cadherin-17; BILL-cadherin; LI-cadherin; P130; Cdh17; CDH16; HPT-1; cadherin-16; FLJ26931; MGC138218; MGC142024
Accession	Q12864-1
Species	Human
Biotinylated	no
Amino Acid Range	Gln23-Met787
Molecular Weight	The protein has a predicted MW of 86.1 kDa. Due to glycosylation, the protein migrates to 90-115 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human CDH17, His Tag at 1 ug/ml (100 ul/Well) on the plate. Dose response curve for Anti-CDH17 Antibody, hFc Tag with the EC50 of 4.1 ng/ml determined by ELISA. See testing image for detail.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 0.01 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human CDH17, His Tag at 1 ug/ml (100 ul/Well) on the plate. Dose response curve for Anti-CDH17 Antibody, hFc Tag with the EC50 of 4.1 ng/ml determined by ELISA.
	Human CDH17 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	Loaded Anti-CDH17 Ab., hFc Tag on ProA-Biosensor can bind Human CDH17, His Tag with an affinity constant of 2.26 nM as determined in BLI assay (Gator® Prime).
	The purity of Human CDH17 is greater than 95% as determined by SEC-HPLC.