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Human CDH9/Cadherin 9 Protein (CDH-HM109) Summary
Product Description |
Recombinant Human CDH9/Cadherin 9 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Gly54-Ala615. |
Product Background |
cadherin-9, a classic type II cadherin expressed exclusively by DG and CA3 neurons in the hippocampus (Bekirov et al., 2002), is required specifically for formation of DG but not CA1 or CA3 synapses in culture. In vivo, loss of cadherin-9 from either DG or CA3 neurons severely disrupts mossy fiber bouton and TE spine formation through trans-synaptic interactions. |
Product Category |
Recombinant Protein / Antibody discovery / Antibody discovery/Others |
Human CDH9/Cadherin 9 Protein (CDH-HM109) Specifications/Details
Protein |
CDH9/Cadherin 9 |
Synonyms |
Cadherin-9; Cadherin9; CDH9 |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Gly54-Ala615 |
Molecular Weight |
The protein has a predicted MW of 64.11 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-His |
Fluorophore |
Unconjugated |
Expression System |
HEK293 |
Purity |
> 80% as determined by Bis-Tris PAGE |
Endotoxin |
Less than 0.1 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
Stability And Storage |
-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Validation Images
|
|
Human CDH9 on Bis-Tris PAGE under reduced condition. The purity is greater than 80%. |
Other Available Proteins:
Finding available proteins...
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