Regular price
$345.00
Order by 4pm ET for delivery on:
Human CEACAM-5/CD66e (35-498) Protein (CAM-HM1D4) Summary
Product Description |
Recombinant Human CEACAM-5/CD66e (35-498) Protein is expressed from HEK293 with His tag at the C-terminus.It contains Lys35-Ala498. |
Product Background |
Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) was identified as a metastatic driver. CEACAM5 overproduction enriched for an epithelial gene expression pattern and facilitated tumor outgrowth at metastatic sites. Tissues from patients with metastatic breast cancer confirmed elevated levels of CEACAM5 in lung metastases relative to breast tumors, and an inverse correlation between CEACAM5 and the mesenchymal marker vimentin was demonstrated. |
Product Category |
Recombinant Protein / Antibody discovery / CAR-T targets, ADC targets |
Human CEACAM-5/CD66e (35-498) Protein (CAM-HM1D4) Specifications/Details
Protein |
CEACAM-5/CD66e |
Synonyms |
CEACAM-5; CD66e; CEA; Meconium antigen 100; Carcinoembryonic; CEACD66e; DKFZp781M2392 |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Lys35-Ala498 |
Molecular Weight |
The protein has a predicted MW of 52.92 kDa. Due to glycosylation, the protein migrates to 80-120 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-His |
Fluorophore |
Unconjugated |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 0.1 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22 um filtered solution in PBS (pH 7.4). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Validation Images
|
|
Human CEACAM-5 (35-498) on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
|
The purity of Human CEACAM-5 (35-498) is greater than 95% as determined by SEC-HPLC. |
Other Available Proteins:
Finding available proteins...
Related Products
Have more questions?
Check out our Frequently Asked Questions page for more details about product specifications, ordering, and shipments.
Contact Us
Recommended Products
Loading...
Recently viewed
