• Express System: HEK293
  • Product Tag: C-hFc (IgG1)
  • Purity: > 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC
  • Amino Acid Range: Lys35-Ala685
Catalog #CAM-HM205
Price
Regular price $0.00
Regular price Sale price $0.00
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Size
Avantor VWR Fisher Scientific

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Human CEACAM-5/CD66e Protein (CAM-HM205) Summary

Product Description

 Recombinant Human CEACAM-5/CD66e Protein is expressed from HEK293 with hFc (IgG1) tag at the C-terminus.It contains Lys35-Ala685.

Product Background

 Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) was identified as a metastatic driver. CEACAM5 overproduction enriched for an epithelial gene expression pattern and facilitated tumor outgrowth at metastatic sites. Tissues from patients with metastatic breast cancer confirmed elevated levels of CEACAM5 in lung metastases relative to breast tumors, and an inverse correlation between CEACAM5 and the mesenchymal marker vimentin was demonstrated.

Product Category

 Recombinant Protein / Antibody discovery / CAR-T targets, ADC targets

Human CEACAM-5/CD66e Protein (CAM-HM205) Specifications/Details

Protein
 CEACAM-5/CD66e
Synonyms
 CEACAM-5; CD66e; CEA; Meconium antigen 100; Carcinoembryonic; CEACD66e; DKFZp781M2392
Accession
Species
 Human
Biotinylated
 no
Amino Acid Range
 Lys35-Ala685
Molecular Weight
 The protein has a predicted MW of 97.27 kDa. Due to glycosylation, the protein migrates to 160-200 kDa based on Bis-Tris PAGE result.
Product Tag
 C-hFc (IgG1)

Fluorophore

 Unconjugated
Expression System
 HEK293
Purity
 > 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC
Endotoxin
 Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
 Liquid
Shipping
 Shipped with dry ice.
Formulation
 Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage
 Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Human CEACAM-5 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human CEACAM-5 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human CEACAM-5 is greater than 90% as determined by SEC-HPLC. The purity of Human CEACAM-5 is greater than 90% as determined by SEC-HPLC.
Other Available Proteins:
Finding available proteins...
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