Human CEACAM-5/CD66e Protein (CAM-HM205)

Immobilized Human CEACAM-5, hFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-CEACAM-5 Antibody, hFc Tag with the EC50 of 25.8ng/ml determined by ELISA.

Human CEACAM-5 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Human CEACAM-5 is greater than 90% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-hFc (IgG1)
Purity: > 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC
Activity: Immobilized Human CEACAM-5, hFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-CEACAM-5 Antibody, hFc Tag with the EC50 of 25.8ng/ml determined by ELISA.
Amino Acid Range: Lys35-Ala685

Catalog #CAM-HM205

Price

$270⁰⁰

Size

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Human CEACAM-5/CD66e Protein (CAM-HM205) Summary

Product Description

Recombinant Human CEACAM-5/CD66e Protein is expressed from HEK293 with hFc (IgG1) tag at the C-terminus.It contains Lys35-Ala685.

Product Background

Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) was identified as a metastatic driver. CEACAM5 overproduction enriched for an epithelial gene expression pattern and facilitated tumor outgrowth at metastatic sites. Tissues from patients with metastatic breast cancer confirmed elevated levels of CEACAM5 in lung metastases relative to breast tumors, and an inverse correlation between CEACAM5 and the mesenchymal marker vimentin was demonstrated.

Human CEACAM-5/CD66e Protein (CAM-HM205) Specifications/Details

Protein	CEACAM-5/CD66e
Synonyms	CEACAM-5; CD66e; CEA; Meconium antigen 100; Carcinoembryonic; CEACD66e; DKFZp781M2392;CEACAM5
Accession	P06731
Species	Human
Biotinylated	no
Amino Acid Range	Lys35-Ala685
Molecular Weight	The protein has a predicted MW of 97.27 kDa. Due to glycosylation, the protein migrates to 160-200 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human CEACAM-5, hFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-CEACAM-5 Antibody, hFc Tag with the EC50 of 25.8ng/ml determined by ELISA.
Product Tag	C-hFc (IgG1)
Fluorophore	Unconjugated
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage	Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

	Immobilized Human CEACAM-5, hFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-CEACAM-5 Antibody, hFc Tag with the EC50 of 25.8ng/ml determined by ELISA.
	Human CEACAM-5 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human CEACAM-5 is greater than 90% as determined by SEC-HPLC.