Human CEACAM-7 Protein (CEA-HM207)

  • Express System: HEK293
  • Product Tag: C-hFc
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Human CEACAM-3, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human CEACAM-7, hFc Tag with the EC50 of 26.5ng/ml determined by ELISA. See testing image for detail.
  • Exact Sequence: Thr36-Ser242

Catalog: CEA-HM207

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Product Description Recombinant Human CEACAM-7 Protein is expressed from HEK293 with hFc tag at the C-terminus.It contains Thr36-Ser242.

Product Background

Carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) belong to a group of mammalian immunoglobulin-related glycoproteins. They are involved in cell–cell recognition and modulate cellular processes that range from the shaping of tissue architecture and neovascularization to the regulation of insulin homeostasis and T-cell proliferation. CEACAM7 (CGM2), a member of the CEA family of proteins with expression restricted to the colon and pancreas, as a potential CAR T-cell target for PDAC.

Product Category

Recombinant Protein

Target

CEACAM-7
Accession

Species

Human

Exact Sequence

Thr36-Ser242
Molecular Weight The protein has a predicted MW of 50.11 kDa. Due to glycosylation, the protein migrates to 68-78 kDa based on Tris-Bis PAGE result.

Activity

Immobilized Human CEACAM-3, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human CEACAM-7, hFc Tag with the EC50 of 26.5ng/ml determined by ELISA. See testing image for detail.

Product Tag

C-hFc

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Immobilized Human CEACAM-3, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human CEACAM-7, hFc Tag with the EC50 of 26.5ng/ml determined by ELISA.
The purity of Human CEACAM-7 is greater than 95% as determined by SEC-HPLC.
Human CEACAM-7 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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