Name: Human CEACAM-8/CD66b Protein (CEA-HM108)
Brand: KactusBio
SKU: CEA-HM108-100UG
Price: 264.0 USD
Availability: InStock

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: The affinity constant of 4.59 uM as determined in SPR assay (Biacore T200).
Amino Acid Range: Gln35-Ser319

Catalog #CEA-HM108

Size

100UG

500UG

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Human CEACAM-8/CD66b Protein (CEA-HM108) Summary

Product Description	Recombinant Human CEACAM-8/CD66b Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln35-Ser319.
Product Background	Eosinophils and their products are likely important in the pathophysiology of allergic diseases, such as bronchial asthma, and in host immunity to parasitic organisms. CD66b (CEACAM8, CGM6, NCA-95) is a single chain, GPI-anchored, highly glycosylated protein belonging to the carcinoembryonic Ag supergene family. CD66b is an activation marker for human granulocytes.
Product Category	Recombinant Protein / Antibody discovery / CAR-T targets

Human CEACAM-8/CD66b Protein (CEA-HM108) Specifications/Details

Protein	CEACAM-8/CD66b
Synonyms	CD66b; CEACAM8; CGM6; CD67; NCA-95
Accession	NP_001807.2
Species	Human
Biotinylated	no
Amino Acid Range	Gln35-Ser319
Molecular Weight	The protein has a predicted MW of 32.5 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result.
Activity	The affinity constant of 4.59 uM as determined in SPR assay (Biacore T200).
Product Tag	C-His
Fluorophore	Unconjugated
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Human CEACAM-8, His Tag immobilized on CM5 Chip can bind Human CEACAM-6, His Tag with an affinity constant of 4.59 uM as determined in SPR assay (Biacore T200).
	Human CEACAM-8 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human CEACAM-8 is greater than 95% as determined by SEC-HPLC.

Other Available Proteins:

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