Human Claudin 4 Protein-Nanodisc (CLD4-HM1N161)
  • Express System: HEK293
  • Product Tag: C-His
  • Activity: Immobilized Human Claudin 4 Nanodisc, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-Claudin 4 Antibody, hFc Tag with the EC50 of 0.13ug/ml determined by ELISA. See testing image for detail.
  • Amino Acid Range: Met1-Val209
Catalog #CLD4-HM1N161
Regular price $1,313.00
/
Size

Order now, ships by:

Product Description

Recombinant Human Claudin 4 Protein-Nanodisc is expressed from HEK293 with His tag at the C-terminus.It contains Met1-Val209.

Product Background

Claudin-4 (CLDN4) is a key component of tight junctions (TJs) in epithelial cells. CLDN4 is overexpressed in many epithelial malignancies and correlates with cancer progression. Changes in CLDN4 expression have been associated with epigenetic factors (such as hypomethylation of promoter DNA), inflammation associated with infection and cytokines, and growth factor signaling. CLDN4 helps to maintain the tumor microenvironment by forming TJs and acts as a barrier to the entry of anticancer drugs into tumors.

Product Category

Recombinant Protein / Antibody discovery / Multiple transmembrane proteins / Nanodisc

Protein

Claudin 4

Synonyms

Claudin-4; CLDN4; Claudin4; CPE-R; CPE R; CPETR1; WBSCR8

Accession

Species

Human

Biotinylated

no

Amino Acid Range

Met1-Val209

Molecular Weight

The protein has a predicted MW of 23.31 kDa.

Activity

Immobilized Human Claudin 4 Nanodisc, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-Claudin 4 Antibody, hFc Tag with the EC50 of 0.13ug/ml determined by ELISA. See testing image for detail.

Product Tag

C-His

Expression System

HEK293

Endotoxin

Less than 1EU per ug by the LAL method.
Form
Liquid
Shipping
Shipped with dry ice.
Formulation
Supplied as 0.22 um filtered solution in PBS (pH 7.4). Notice: Not recommended for immunization.
Stability And Storage
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Human Claudin 4 Nanodisc, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-Claudin 4 Antibody, hFc Tag with the EC50 of 0.13ug/ml determined by ELISA. Immobilized Human Claudin 4 Nanodisc, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-Claudin 4 Antibody, hFc Tag with the EC50 of 0.13ug/ml determined by ELISA.

Have more questions?

Check out our Frequently Asked Questions page for more details about product specifications, ordering, and shipments.

Contact Us

support@kactusbio.us

Recently viewed