Name: Human Claudin 4 Protein-VLP (CLD-HM104)
Brand: KactusBio
SKU: CLD-HM104-100UG
Price: 1210.0 USD
Availability: InStock

Immobilized Human Claudin 4 VLP at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-Claudin 4 Antibody, hFc Tag with the EC50 of 6.5ng/ml determined by ELISA (QC Test).

The purity of Human Claudin 4 VLP is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Purity: > 95% as determined by HPLC
Activity: Immobilized Human Claudin 4 VLP at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-Claudin 4 Antibody, hFc Tag with the EC50 of 6.5ng/ml determined by ELISA (QC Test). See testing image for detail.
Amino Acid Range: Met1-Val209

Catalog #CLD-HM104

Size

100UG

100UG X 5

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Product Description	Recombinant Human Claudin 4 Protein-VLP is expressed from HEK293.It contains Met1-Val209.
Product Background	Claudin-4 (CLDN4) is a key component of tight junctions (TJs) in epithelial cells. CLDN4 is overexpressed in many epithelial malignancies and correlates with cancer progression. Changes in CLDN4 expression have been associated with epigenetic factors (such as hypomethylation of promoter DNA), inflammation associated with infection and cytokines, and growth factor signaling. CLDN4 helps to maintain the tumor microenvironment by forming TJs and acts as a barrier to the entry of anticancer drugs into tumors.
Product Category	Recombinant Protein / Antibody discovery / Multiple transmembrane proteins / VLP

Protein	Claudin 4
Synonyms	Claudin-4; CLDN4; Claudin4; CPE-R; CPE R; CPETR1; WBSCR8
Accession	O14493
Species	Human
Biotinylated	no
Amino Acid Range	Met1-Val209
Molecular Weight	The target protein has a predicted MW of 23.31 kDa.
Activity	Immobilized Human Claudin 4 VLP at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-Claudin 4 Antibody, hFc Tag with the EC50 of 6.5ng/ml determined by ELISA (QC Test). See testing image for detail.
Expression System	HEK293
Purity	> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22um filtered solution in PBS, 300mM L-Arginine (pH 7.4). Notice: If you need it for immunization, water-soluble adjuvant is recommended.
Stability And Storage	Valid for 12 months from date of receipt when stored at -80°C.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human Claudin 4 VLP at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-Claudin 4 Antibody, hFc Tag with the EC50 of 6.5ng/ml determined by ELISA (QC Test).
	The purity of Human Claudin 4 VLP is greater than 95% as determined by SEC-HPLC.