Human Claudin 6 Protein-VLP (CLD-HM006)

  • Express System: HEK293
  • Purity: > 95% as determined by HPLC.
  • Activity: Immobilized Human Claudin 6 VLP at 5ug/ml (100ul/Well). Dose response curve for Anti-Claudin 6 Antibody, mFc Tag with the EC50 of 2.5ng/ml determined by ELISA (QC Test). The affinity constant of 0.36 nM as determined in SPR assay (Biacore T200). See testing image for detail.
  • Exact Sequence: Met1-Val220

Catalog: CLD-HM006

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Product Description Recombinant Full length Human Claudin 6 Protein-VLP is expressed from HEK293.It contains Met1-Val220.

Product Background

Claudin-6 is a multipass transmembrane protein in the Claudin family. Claudin-6 is expressed by epithelial cells where it participates in tissue development and the maintenance of tight junction integrity. Human Claudin-6 shares 88% and 86% amino acid sequence identity with mouse and rat Claudin-6, respectively.

Product Category

Recombinant Protein

Target

Claudin 6
Synonyms Claudin-6; Skullin; CLDN6; Claudin6; Skullin 2

Gene/Protein ID

P56747

Species

Human

Exact Sequence

Met1-Val220
Molecular Weight The target protein has a predicted MW of 24.5 kDa.

Activity

Immobilized Human Claudin 6 VLP at 5ug/ml (100ul/Well). Dose response curve for Anti-Claudin 6 Antibody, mFc Tag with the EC50 of 2.5ng/ml determined by ELISA (QC Test). The affinity constant of 0.36 nM as determined in SPR assay (Biacore T200). See testing image for detail.

Express System

HEK293
Purity > 95% as determined by HPLC.
Endotoxin Less than 1EU per ug by the LAL method.
Form Liquid
Shipping Shipped with dry ice.
Formulation Supplied as 0.22um filtered solution in PBS (pH 7.4). Notice: If you need it for immunization, Do Not use any adjuvant.
Stability And Storage Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Human Claudin 6 VLP immobilized on CM5 Chip can bind Anti-Claudin 6 Antibody with an affinity constant of 0.36 nM as determined in SPR assay (Biacore T200).
Immobilized Human Claudin 6 VLP at 5ug/ml (100ul/Well). Dose response curve for Anti-Claudin 6 Antibody, mFc Tag with the EC50 of 2.5ng/ml determined by ELISA (QC Test).
The purity of Human Claudin 6 VLP is greater than 95% as determined by SEC-HPLC.

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