Name: Human CLEC-1 Protein (CLE-HM201)
Brand: KactusBio
SKU: CLE-HM201-100UG
Price: 297.0 USD
Availability: InStock

Express System: HEK293
Product Tag: N-hFc
Purity: > 95% as determined by Bis-Tris PAGE
Activity: Immobilized Human CLEC-1, hFc Tag at 0.5ug/ml (100ul/Well) on the plate. Dose response curve for Biotinylated Anti-CLEC-1 Antibody, hFc Tag with the EC50 8.8ng/ml determined by ELISA. See testing image for detail.
Amino Acid Range: Gln74-Asp280

Catalog #CLE-HM201

Size

100UG

500UG

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Product Description	Recombinant Human CLEC-1 Protein is expressed from HEK293 with hFc tag at the N-Terminus.It contains Gln74-Asp280.
Product Background	C-type lectin-like receptor-1 (CLEC-1) is a member of the Dectin-1 cluster of pattern recognition receptors (PRRs). It is involved in host immunity, has immunoregulatory function, and supports allograft tolerance. CLEC-1 may act as a negative regulator of Dectin-1 induced host inflammatory response via suppressing neutrophils recruitment and production of pro-inflammatory cytokine IL-1β production in response to A. fumigatus keratitis.
Product Category	Recombinant Protein / Antibody discovery

Protein	CLEC-1
Synonyms	CLEC-1; CLEC1; CLEC1A; MGC34328
Accession	Q8NC01
Species	Human
Biotinylated	no
Amino Acid Range	Gln74-Asp280
Molecular Weight	The protein has a predicted MW of 51.2 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human CLEC-1, hFc Tag at 0.5ug/ml (100ul/Well) on the plate. Dose response curve for Biotinylated Anti-CLEC-1 Antibody, hFc Tag with the EC50 8.8ng/ml determined by ELISA. See testing image for detail.
Product Tag	N-hFc
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human CLEC-1, hFc Tag at 0.5ug/ml (100ul/Well) on the plate. Dose response curve for Biotinylated Anti-CLEC-1 Antibody, hFc Tag with the EC50 8.8ng/ml determined by ELISA.
	Human CLEC-1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.