Product Description |
Recombinant Human CLEC4A/DCIR Protein is expressed from HEK293 with His tag at the C-terminus.It contains Gln70-Leu237. |
Product Background |
Clec4a has been reported to be an immune suppressor of dendritic cells (DCs), but its potential role in cancer therapy remains to be elucidated. silencing of Clec4a2 expression via skin delivery of shRNA produces an effective antitumor response and that Clec4a2 shRNA may have therapeutic potential as an adjuvant for cancer immunotherapy. |
Product Category |
Recombinant Protein |
Target |
CLEC4A/DCIR |
Synonyms |
CD367; Clec4a2; CLECSF6; DCIR; DDB27; HDCGC13P; LLIR; CLEC4A; DCIRLLIR |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Gln70-Leu237 |
Molecular Weight |
The protein has a predicted MW of 21.47 kDa. Due to glycosylation, the protein migrates to 27-35 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-His |
Express System |
HEK293 |
Purity |
>95% as determined by Bis-Tris PAGE;>95% as determined by HPLC |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22 um filtered solution in PBS (pH 7.4). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
|
|
Human CLEC4A on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
|
The purity of Human CLEC4A is greater than 95% as determined by SEC-HPLC. |
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