Name: Human CLEC4A/DCIR Protein (CLE-HM24A)
Brand: KactusBio
SKU: CLE-HM24A-100UG
Price: 297.0 USD
Availability: InStock

Express System: HEK293
Product Tag: C-hFc
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Human CLEC4A, hFc Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Biotinylated Anti-CLEC4A Antibody, hFc Tag with the EC50 of 29.8ng/ml determined by ELISA. See testing image for detail.
Amino Acid Range: Gln70-Leu237

Catalog #CLE-HM24A

Size

100UG

500UG

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Product Description	Recombinant Human CLEC4A/DCIR Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Gln70-Leu237.
Product Background	Clec4a has been reported to be an immune suppressor of dendritic cells (DCs), but its potential role in cancer therapy remains to be elucidated. silencing of Clec4a2 expression via skin delivery of shRNA produces an effective antitumor response and that Clec4a2 shRNA may have therapeutic potential as an adjuvant for cancer immunotherapy.
Product Category	Recombinant Protein / Antibody discovery

Protein	CLEC4A/DCIR
Synonyms	CD367; Clec4a2; CLECSF6; DCIR; DDB27; HDCGC13P; LLIR; CLEC4A; DCIRLLIR
Accession	Q9UMR7-1
Species	Human
Biotinylated	no
Amino Acid Range	Gln70-Leu237
Molecular Weight	The protein has a predicted MW of 46.7 kDa. Due to glycosylation, the protein migrates to 60-65 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human CLEC4A, hFc Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Biotinylated Anti-CLEC4A Antibody, hFc Tag with the EC50 of 29.8ng/ml determined by ELISA. See testing image for detail.
Product Tag	C-hFc
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 24 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human CLEC4A, hFc Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Biotinylated Anti-CLEC4A Antibody, hFc Tag with the EC50 of 29.8ng/ml determined by ELISA.
	Human CLEC4A on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human CLEC4A is greater than 95% as determined by SEC-HPLC.