Human CLEC4A/DCIR Protein (CLE-HM24A)
Human CLEC4A/DCIR Protein (CLE-HM24A)
Human CLEC4A/DCIR Protein (CLE-HM24A)
Human CLEC4A/DCIR Protein (CLE-HM24A)
  • Express System: HEK293
  • Product Tag: C-hFc
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Human CLEC4A, hFc Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Biotinylated Anti-CLEC4A Antibody, hFc Tag with the EC50 of 29.8ng/ml determined by ELISA. See testing image for detail.
  • Amino Acid Range: Gln70-Leu237
Catalog #CLE-HM24A
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Product Description
 Recombinant Human CLEC4A/DCIR Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Gln70-Leu237.
Product Background
 Clec4a has been reported to be an immune suppressor of dendritic cells (DCs), but its potential role in cancer therapy remains to be elucidated. silencing of Clec4a2 expression via skin delivery of shRNA produces an effective antitumor response and that Clec4a2 shRNA may have therapeutic potential as an adjuvant for cancer immunotherapy.
Product Category
 Recombinant Protein
Target
 CLEC4A/DCIR
Synonyms
 CD367; Clec4a2; CLECSF6; DCIR; DDB27; HDCGC13P; LLIR; CLEC4A; DCIRLLIR
Accession
Species
 Human
Biotinylated
 no
Amino Acid Range
 Gln70-Leu237
Molecular Weight
 The protein has a predicted MW of 46.7 kDa. Due to glycosylation, the protein migrates to 60-65 kDa based on Bis-Tris PAGE result.
Activity
 Immobilized Human CLEC4A, hFc Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Biotinylated Anti-CLEC4A Antibody, hFc Tag with the EC50 of 29.8ng/ml determined by ELISA. See testing image for detail.
Product Tag
 C-hFc
Express System
 HEK293
Purity
 > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
 Less than 1EU per ug by the LAL method.
Form
 Lyophilized
Shipping
 Shipped at ambient temperature.
Formulation
 Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
 Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
 Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Immobilized Human CLEC4A, hFc Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Biotinylated Anti-CLEC4A Antibody, hFc Tag with the EC50 of 29.8ng/ml determined by ELISA.
Human CLEC4A on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human CLEC4A is greater than 95% as determined by SEC-HPLC.
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