- Express System: HEK293
- Product Tag: N-His
- Purity: > 95% as determined by Bis-Tris PAGE
- Activity: Immobilized Human CLEC7A, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-CLEC7A Antibody, hFc Tag with the EC50 of 1.3ng/ml determined by ELISA.
- Amino Acid Range: Thr66-Met201
Human CLEC7A Protein (CLE-HM17A) Summary
Product Description |
Recombinant Human CLEC7A Protein is expressed from HEK293 with His tag at the N-terminus.It contains Thr66-Met201. |
Product Background |
Dendritic cell-associated C-type lectin-1 (Dectin-1), also known as β-glucan receptor is an emerging pattern recognition receptor (PRR) which belongs to the family of C-type lectin receptor (CLR). Dectin-1 signaling axis has been suggested to be targeted as an effective therapeutic strategy for cancers. Dectin-1 has also been elucidated ascetically in the heart, respiratory, intestinal, neurological and developmental disorders. |
Human CLEC7A Protein (CLE-HM17A) Specifications/Details
Protein |
CLEC7A |
Synonyms |
Beta-glucan receptor; DC-associated C-type lectin 1; Dectin-1; Dectin1; CD369; BGR; CLECSF12; DECTIN1; CANDF4 |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Thr66-Met201 |
Molecular Weight |
The protein has a predicted MW of 16.58 kDa. Due to glycosylation, the protein migrates to 15-20 kDa based on Bis-Tris PAGE result. |
Activity |
Immobilized Human CLEC7A, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-CLEC7A Antibody, hFc Tag with the EC50 of 1.3ng/ml determined by ELISA. |
Product Tag |
N-His |
Fluorophore |
Unconjugated |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22 um filtered solution in PBS (pH 7.4). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Other Available Proteins: