Human Clusterin Protein, Ultra Low Endotoxin (CLN-HM101-UL)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE
  • Activity: Immobilized Human Clusterin, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-Clusterin Antibody, hFc Tag with the EC50 of 9.0ng/ml determined by ELISA (QC Test). See testing image for detail.
  • Amino Acid Range: Asp23-Glu449
Catalog #CLN-HM101-UL
Regular price $327.00
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Product Description

Recombinant Human Clusterin Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Asp23-Glu449.

Product Background

Clusterin (CLU) is a stress-activated, ATP-independent molecular chaperone, normally secreted from cells, that is up-regulated in Alzheimer disease and in many cancers. It plays important roles in protein homeostasis/proteostasis, inhibition of cell death pathways, and modulation of pro-survival signalling and transcriptional networks. Changes in the CLU gene locus are highly associated with Alzheimer disease, and many therapy-resistant cancers over-express CLU.

Product Category

Recombinant Protein / Antibody discovery / Antibody discovery | Others

Protein

Clusterin

Synonyms

Clusterin; Apo-J; Clustrin; SGP-2; Msgp-2; CLU; AAG4; APOJ; CLI; KUB1; SP-40; TRPM2; CLI; KUB1;

Accession

Species

Human

Biotinylated

no

Amino Acid Range

Asp23-Glu449

Molecular Weight

The protein has a predicted MW of 51.2 kDa. The protein migrates to 38-41 kDa based on Bis-Tris PAGE result.

Activity

Immobilized Human Clusterin, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-Clusterin Antibody, hFc Tag with the EC50 of 9.0ng/ml determined by ELISA (QC Test). See testing image for detail.

Product Tag

C-His

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE

Endotoxin

Less than 0.01 EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
-20 to -80°C for 24 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Human Clusterin, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-Clusterin Antibody, hFc Tag with the EC50 of 9.0ng/ml determined by ELISA (QC Test). Immobilized Human Clusterin, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-Clusterin Antibody, hFc Tag with the EC50 of 9.0ng/ml determined by ELISA (QC Test).
Human Clusterin on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human Clusterin on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

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support@kactusbio.us

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