Name: Human Complement C1s Protein (C1S-HM101)
Brand: KactusBio
SKU: C1S-HM101-100UG
Price: 315.0 USD
Availability: InStock

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE
Activity: Immobilized Human Complement C1s, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-C1S Antibody, hFc Tag with the EC50 of 9.6ng/ml determined by ELISA (QC Test). See testing image for detail.
Amino Acid Range: Glu16-Asp688

Catalog #C1S-HM101

Size

100UG

500UG

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Product Description	Recombinant Human Complement C1s Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu16-Asp688.
Product Background	Complement C1s protease inhibitors have potential utility in the treatment of diseases associated with activation of the classical complement pathway such as humorally mediated graft rejection, ischemia-reperfusion injury (IRI), vascular leak syndrome, and acute respiratory distress syndrome (ARDS).
Product Category	Recombinant Protein / Antibody discovery

Protein	Complement C1s
Synonyms	EDSPD2; C1 esterase;Complement Component C1s
Accession	P09871
Species	Human
Biotinylated	no
Amino Acid Range	Glu16-Asp688
Molecular Weight	The protein has a predicted MW of 75.98 kDa. Due to enzyme lysis glycosylation, the protein migrates to 55-60 kDa (light chain), 32-35 kDa (heavy chain) and 76-96 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human Complement C1s, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-C1S Antibody, hFc Tag with the EC50 of 9.6ng/ml determined by ELISA (QC Test). See testing image for detail.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human Complement C1s, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-C1S Antibody, hFc Tag with the EC50 of 9.6ng/ml determined by ELISA (QC Test).
	Human Complement C1s on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.