Product Description |
Recombinant Human Complement Component C2 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala21-Leu752. |
Product Background |
Single nucleotide polymorphism (SNP) of complement component 2 (C2) has been found to be significantly associated with hepatocellular carcinoma (HCC). Significantly lower C2 expression was found at HCC compared to healthy controls, and C2 was associated with TNM stages. Higher C2 expression was significantly associated with better prognosis, and multivariate analysis showed that C2 was also an independent factor for the prognosis of HCC. |
Product Category |
Recombinant Protein |
Target |
Complement Component C2 |
Synonyms |
Complement C2; C3/C5 convertase; C2; ARMD14; CO2 |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Ala21-Leu752 |
Molecular Weight |
The protein has a predicted MW of 82.2 kDa (Pro form). Due to glycosylation, the protein migrates to 83-90 kDa (Pro form) based on Bis-Tris PAGE result. |
Product Tag |
C-His |
Express System |
HEK293 |
Purity |
>95% as determined by Bis-Tris PAGE;>95% as determined by HPLC |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage |
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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