Product Description |
Recombinant Human Complement C2 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala21-Leu752. |
Product Background |
Single nucleotide polymorphism (SNP) of complement component 2 (C2) has been found to be significantly associated with hepatocellular carcinoma (HCC). Significantly lower C2 expression was found at HCC compared to healthy controls, and C2 was associated with TNM stages. Higher C2 expression was significantly associated with better prognosis, and multivariate analysis showed that C2 was also an independent factor for the prognosis of HCC. |
Product Category |
Recombinant Protein / Antibody discovery / Antibody discovery | Others |
Protein |
Complement C2 |
Synonyms |
Complement Component C2; C3/C5 convertase; C2; ARMD14; CO2 |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Ala21-Leu752 |
Molecular Weight |
The protein has a predicted MW of 82.2 kDa. Due to glycosylation, the protein migrates to 83-90 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-His |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
Stability And Storage |
-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
|
|
Human Complement C2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
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The purity of Human Complement C2 is greater than 95% as determined by SEC-HPLC. |
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