Human Complement Component C2 Protein (CC2-HM101)

  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Exact Sequence: Ala21-Leu752

Catalog: CC2-HM101

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Product Description Recombinant Human Complement Component C2 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala21-Leu752.

Product Background

Single nucleotide polymorphism (SNP) of complement component 2 (C2) has been found to be significantly associated with hepatocellular carcinoma (HCC). Significantly lower C2 expression was found at HCC compared to healthy controls, and C2 was associated with TNM stages. Higher C2 expression was significantly associated with better prognosis, and multivariate analysis showed that C2 was also an independent factor for the prognosis of HCC.

Product Category

Recombinant Protein

Target

Complement Component C2
Synonyms Complement C2; C3/C5 convertase; C2; ARMD14; CO2

Gene/Protein ID

P06681-1

Species

Human

Exact Sequence

Ala21-Leu752
Molecular Weight The protein has a predicted MW of 82.2 kDa (Pro form). Due to glycosylation, the protein migrates to 83-90 kDa (Pro form) based on Tris-Bis PAGE result.

Product Tag

C-His

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Measured by its ability to cleave a colorimetric peptide substrate, N-carbobenzyloxy-Gly-Arg-ThioBenzyl ester (Z-GR-SBzl), in the presence of 5,5'Dithio-bis (2-nitrobenzoic acid) (DTNB). The specific activity is >100 pmol/min/µg.
The purity of Human Complement Component C2 is greater than 95% as determined by SEC-HPLC.
Human Complement Component C2 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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