Human CXCL13/BCA-1 Protein (CXC-HM213)
Human CXCL13/BCA-1 Protein (CXC-HM213)
Human CXCL13/BCA-1 Protein (CXC-HM213)
  • Express System: HEK293
  • Product Tag: N-hFc
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Human CXCL13, hFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-CXCL13 Antibody, hFc Tag with the EC50 of 31.3ng/ml determined by ELISA (QC Test). See testing image for detail.
  • Amino Acid Range: Val23-Per109
Catalog #CXC-HM213
Regular price $330.00
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Human CXCL13/BCA-1 Protein (CXC-HM213) Summary

Product Description

Recombinant Human CXCL13/BCA-1 Protein is expressed from HEK293 with hFc tag at the N-Terminus.It contains Val23-Per109.

Product Background

Recent studies have implicated chemokines in microglial activation and pathogenesis of neuropathic pain. C-X-C motif chemokine 13 (CXCL13) is a B lymphocyte chemoattractant that activates CXCR5. Using the spinal nerve ligation (SNL) model of neuropathic pain, CXCL13 was persistently upregulated in spinal cord neurons after SNL, resulting in spinal astrocyte activation via CXCR5 in mice.

Product Category

Recombinant Protein / Antibody discovery / Antibody discovery | Others

Human CXCL13/BCA-1 Protein (CXC-HM213) Specifications/Details

Protein
CXCL13/BCA-1
Synonyms
ANGIE; ANGIE2; BCA-1; BCA1; BLC; BLR1L; SCYB13
Accession
Species
Human
Biotinylated
no
Amino Acid Range
Val23-Per109
Molecular Weight
The protein has a predicted MW of 37.6 kDa. Due to glycosylation, the protein migrates to 42-50 kDa based on Bis-Tris PAGE result.
Activity
Immobilized Human CXCL13, hFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-CXCL13 Antibody, hFc Tag with the EC50 of 31.3ng/ml determined by ELISA (QC Test). See testing image for detail.

Product Tag

N-hFc
Expression System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1 EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Human CXCL13, hFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-CXCL13 Antibody, hFc Tag with the EC50 of 31.3ng/ml determined by ELISA (QC Test). Immobilized Human CXCL13, hFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-CXCL13 Antibody, hFc Tag with the EC50 of 31.3ng/ml determined by ELISA (QC Test).
Human CXCL13 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human CXCL13 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human CXCL13/BCA-1 Protein is greater than 95% as determined by SEC-HPLC. The purity of Human CXCL13/BCA-1 Protein is greater than 95% as determined by SEC-HPLC.
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