Human CXCL13/BCA-1 Protein (CXC-HM213)
Human CXCL13/BCA-1 Protein (CXC-HM213)
Human CXCL13/BCA-1 Protein (CXC-HM213)
Human CXCL13/BCA-1 Protein (CXC-HM213)
  • Express System: HEK293
  • Product Tag: N-hFc
  • Purity: > 95% as determined by Bis-Tris PAGE
  • Activity: Immobilized Human CXCL13, hFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-CXCL13 Antibody, hFc Tag with the EC50 of 23.8ng/ml determined by ELISA. See testing image for detail.
  • Amino Acid Range: Val23-Per109
Catalog #CXC-HM213
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Product Description
 Recombinant Human CXCL13/BCA-1 Protein is expressed from HEK293 with hFc tag at the N-Terminus.It contains Val23-Per109.
Product Background
 Recent studies have implicated chemokines in microglial activation and pathogenesis of neuropathic pain. C-X-C motif chemokine 13 (CXCL13) is a B lymphocyte chemoattractant that activates CXCR5. Using the spinal nerve ligation (SNL) model of neuropathic pain, CXCL13 was persistently upregulated in spinal cord neurons after SNL, resulting in spinal astrocyte activation via CXCR5 in mice.
Product Category
 Recombinant Protein
Target
 CXCL13/BCA-1
Synonyms
 ANGIE; ANGIE2; BCA-1; BCA1; BLC; BLR1L; SCYB13
Accession
Species
 Human
Biotinylated
 no
Amino Acid Range
 Val23-Per109
Molecular Weight
 The protein has a predicted MW of 37.6 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Bis-Tris PAGE result.
Activity
 Immobilized Human CXCL13, hFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-CXCL13 Antibody, hFc Tag with the EC50 of 23.8ng/ml determined by ELISA. See testing image for detail.
Product Tag
 N-hFc
Express System
 HEK293
Purity
 > 95% as determined by Bis-Tris PAGE
Endotoxin
 Less than 1EU per ug by the LAL method.
Form
 Lyophilized
Shipping
 Shipped at ambient temperature.
Formulation
 Lyophilized from 0.22 um filtered solution in 50mM Tris, 500mM NaCl (pH 7.4). Normally 8% mannitol is added as protectant before lyophilization.
Reconstitution
 Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
 Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Immobilized Human CXCL13, hFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-CXCL13 Antibody, hFc Tag with the EC50 of 23.8ng/ml determined by ELISA.
Human CXCL13 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
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