Product Description |
Recombinant Human CXCL16 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Asn30-Thr205. |
Product Background |
CXC chemokine ligand 16 (CXCL16) is a CXC soluble chemokine, an adhesion molecule and a cell surface scavenger receptor. CXCL16 regulates inflammation, tissue injury and fibrosis. Parenchymal renal cells, vascular wall cells, leukocytes and platelets express and/or release CXCL16 under the regulation of inflammatory mediators. CXCL16 expression is increased in experimental and human nephropathies. Targeting CXCL16 protected from experimental glomerular injury or interstitial fibrosis. |
Product Category |
Recombinant Protein / Antibody discovery / Antibody discovery | Others |
Protein |
CXCL16 |
Synonyms |
SR-PSOX; CXCLG16; SRPSOX; CXCL16; SCYB16 |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Asn30-Thr205 |
Molecular Weight |
The protein has a predicted MW of 45.9 kDa. Due to glycosylation, the protein migrates to 70-90 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-hFc |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
Stability And Storage |
-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
|
|
Human CXCL16 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
|
The purity of Human CXCL16 is greater than 90% as determined by SEC-HPLC. |
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