SEC-HPLC chromatogram with a sharp peak at 8.4 minutes and a minor pre-peak at 7.5 minutes, indicating high purity with minimal aggregation of the protein sample.
Human CXCL4L1 Protein (CXC-HM2L1)
SEC-HPLC chromatogram with a sharp peak at 8.4 minutes and a minor pre-peak at 7.5 minutes, indicating high purity with minimal aggregation of the protein sample.
Human CXCL4L1 Protein (CXC-HM2L1)
  • Express System: HEK293
  • Product Tag: C-hFc (IgG1)
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Phe31-Ser104
Catalog #CXC-HM2L1
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Size
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Human CXCL4L1 Protein (CXC-HM2L1) Summary

Product Description

 Recombinant Human CXCL4L1 Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Phe31-Ser104.

Product Background

 Platelet factor-4 (CXCL4/PF-4) was the first chemokine shown to inhibit angiogenesis. CXCL4L1/PF-4var, recently isolated from thrombin-stimulated platelets, differing from authentic CXCL4/PF-4 in three carboxy-terminally located amino acids, was found to be more potent than CXCL4/PF-4 in inhibiting angiogenesis and tumor growth. Both glycosaminoglycans (GAG) and CXCR3 are implicated in the activities of the PF-4 variants.

Product Category

 Recombinant Protein / Antibody discovery / Antibody discovery | Others

Human CXCL4L1 Protein (CXC-HM2L1) Specifications/Details

Protein
 CXCL4L1
Synonyms
 Platelet factor 4 variant; CXCL4L1; PF4alt; PF4var1; CXCL4V1; PF4-ALT; PF4A; SCYB4V1
Accession
Species
 Human
Biotinylated
 no
Amino Acid Range
 Phe31-Ser104
Molecular Weight
 The protein has a predicted MW of 35.01 kDa. Due to glycosylation, the protein migrates to 43-48 kDa based on Bis-Tris PAGE result.
Product Tag
 C-hFc (IgG1)

Fluorophore

 Unconjugated
Expression System
 HEK293
Purity
 > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
 Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
 Lyophilized
Shipping
 Shipped at ambient temperature.
Formulation
 Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
 Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
 -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Human CXCL4L1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human CXCL4L1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human CXCL4L1 is greater than 95% as determined by SEC-HPLC. The purity of Human CXCL4L1 is greater than 95% as determined by SEC-HPLC.
Other Available Proteins:
Finding available proteins...
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