Human CXCL4L1 Protein (CXC-HM2L1)
Catalog: CXC-HM2L1
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| Product Description | Recombinant Human CXCL4L1 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Phe31-Ser104. |
Product Background |
Platelet factor-4 (CXCL4/PF-4) was the first chemokine shown to inhibit angiogenesis. CXCL4L1/PF-4var, recently isolated from thrombin-stimulated platelets, differing from authentic CXCL4/PF-4 in three carboxy-terminally located amino acids, was found to be more potent than CXCL4/PF-4 in inhibiting angiogenesis and tumor growth. Both glycosaminoglycans (GAG) and CXCR3 are implicated in the activities of the PF-4 variants. |
Product Category |
Recombinant Protein |
Target |
CXCL4L1 |
Gene/Protein ID |
P10720 |
Species |
Human |
Exact Sequence |
Phe31-Ser104 |
| Molecular Weight | The protein has a predicted MW of 35.01 kDa. Due to glycosylation, the protein migrates to 43-48 kDa based on Tris-Bis PAGE result. |
Product Tag |
C-hFc |
Express System |
HEK293 |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per ug by the LAL method. |
| Form | Lyophilized |
| Shipping | Shipped at ambient temperature. |
| Formulation | Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Stability And Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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The purity of Human CXCL4L1 is greater than 95% as determined by SEC-HPLC. |
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Human CXCL4L1 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
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